This paper explores the concept of Generalized Roughness in LA-Semigroups and its applications in various mathematical disciplines. We highlight the fundamental properties and structures of Generalized Roughness, examining its relationships with Fuzzy Lie Algebras, Order Theory, Lattice Structures, Algebraic Structures, and Categorical Perspectives. Moreover, we investigate the potential of mathematical modeling, optimization techniques, data analysis, and machine learning in the context of Generalized Roughness. Our findings reveal important results in Generalized Roughness, such as the preservation of roughness under the fuzzy equivalence relation and the composition of roughness sets. We demonstrate the significance of Generalized Roughness in the context of order theory and lattice structures, presenting key propositions and a theorem that elucidate its properties and relationships. Furthermore, we explore the applications of Generalized Roughness in mathematical modeling and optimization, highlighting the optimization of roughness measures, parameter estimation, and decision-making processes related to LA-Semigroup operations. We showcase how mathematical techniques can enhance understanding and utilization of LA-Semigroups in practical scenarios. Lastly, we delve into the role of data analysis and machine learning in uncovering patterns, relationships, and predictive models in Generalized Roughness. By leveraging these techniques, we provide examples and insights into how data analysis and machine learning can contribute to enhancing our understanding of LA-Semigroup behavior and supporting decision-making processes.