Gait, posture and cognition in Parkinson's disease

Barbosa, Alessandra Ferreira; Chen, Janini; Freitag, Fernanda; Valente, Debora; Souza, Carolina de; Voos, Mariana Callil; Chien, Hsin Fen

doi:10.1590/s1980-5764-2016dn1004005

Cited by 32 publications

(25 citation statements)

References 55 publications

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“…One study has shown that gait and balance are impaired in patients with Parkinson's, which can lead to severe falls and injuries (17) . Another study showed that these patients also present this type of risk, therefore, they should be referred to early postural rehabilitation in order to improve gait and accordingly prevent falls (18) . This research identified that auditory deficit is related to the high risk of falls.…”

Section: Discussionmentioning

confidence: 99%

Factors associated with the risk of falls in hospitalized adult patients

Bittencourt

Graube

Stumm

et al. 2017

Rev. esc. enferm. USP

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OBJECTIVE Analyzing factors related to the risk of falls in hospitalized adult patients. METHOD A cross-sectional, analytical and quantitative study, developed in Clinical and Surgical Hospitalization Units from June to August 2015. Data collection instruments were sociodemographic and clinical forms, and the Morse Scale. Data were obtained with the patients and from medical records. Absolute and relative frequencies were used in the univariate statistical analysis, and chi-square test in the bivariate analysis. RESULTS 612 patients participated in the study. An association (p<0.001) was found between the high risk of falls and clinical neurological hospitalization, surgical trauma (hospitalization) and comorbidities such as diabetes mellitus, systemic arterial hypertension, visual impairment, vertigo and fear of falling. CONCLUSION An association between the risk of falls was found due to hospitalization, comorbidities and intrinsic factors. Regarding extrinsic factors, an association between mats/carpets and risk of falls was found. No association between the risk of falls with other extrinsic factors was found.

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Section: Discussionmentioning

confidence: 99%

Factors associated with the risk of falls in hospitalized adult patients

Bittencourt

Graube

Stumm

et al. 2017

Rev. esc. enferm. USP

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“…In the present study we aimed to determine the type of gait (FG, BG, or DG) that is most strongly associated with pathophysiological changes reflecting motor symptoms or the risk of falling in patients with de novo PD. We hypothesized that DG is more closely related to motor symptoms and the risk of falling in PD patients because mild cognitive impairment is not uncommon in the early stages of PD,1213 and such cognitive difficulties could exert a greater impact on DG in patients with de novo PD 14. However, it was found that the results did not fully support this hypothesis.…”

Section: Introductionmentioning

confidence: 95%

Backward Gait is Associated with Motor Symptoms and Fear of Falling in Patients withDe NovoParkinson's Disease

et al. 2019

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Background and PurposeMany previous studies have investigated forward gait (FG), backward gait (BG), and dual-task gait (DG) in patients with Parkinson's disease (PD). However, it remains uncertain whether gait parameters are implicated in motor symptoms or the risk of falling, especially in patients with de novo PD.MethodsDemographic and clinical characteristics including the Fear of Falling Measure (FFM) were assessed in patients with de novo PD and in healthy subjects. A computerized gait analysis using the GAITRite system was performed for FG, BG, and DG. The Unified Parkinson's Disease Rating Scale Part III was assessed in patients with PD.ResultsThis prospective study included 24 patients with de novo PD and 27 controls. Compared with controls, patients with de novo PD showed a slower gait and shorter stride in all three gaits. Patients with de novo PD also exhibited increases in the stride-to-stride variability in the stride time and stride length of the gait for BG, increased length for DG, and no increase for FG. Moreover, the BG speed in de novo PD patients was significantly associated with their motor symptoms (bradykinesia, postural instability, gait difficulty, and total motor score) and negatively correlated with the FFM score.ConclusionsThe BG dynamics were more impaired and more closely related to motor symptoms and fear of falling than were the FG or DG dynamics in patients with de novo PD, indicating that BG parameters are potential biomarkers for the progression of PD.

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“…(e.g., memory loss, word-retrieval difficulties) and behavioral (e.g., depression) symptoms become more tightly coupled as worsening balance and gait deficits increasingly restrict patients' independence and quality of life (Barbosa et al, 2016;Bohnen & Cham, 2006;Dirnberger & Jahanshahi, 2013). Indeed, cognitive resources are necessary to process and integrate sensory and motor information and to plan the motor responses for maintaining balance (e.g., Kelly et al, 2015).…”

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confidence: 99%

Memory, subjective memory and motor functioning in non-demented elders with and without Parkinson’s disease

et al. 2019

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Parkinson’s Disease (PD) is a progressive neurological condition characterized by motor and non-motor symptoms impacting life quality. The main aim of the current study was to investigate the effect of PD on objective (i.e., working memory and semantic memory) and subjective memory (i.e., self-reported seriousness of forgetting, mnemonic usage and actual memory efficiency) controlling for the effect of depressive symptomatology. The relationship of working memory performance to gait and mobility indices was also examined, as well as the factors predicting subjective memory were explored. Fifty-four community-dwelling adults (mean age = 72.3 years, SD = 8.8) were recruited in Sardinia, an Italian island located in the Mediterranean Sea. Specifically, 27 non-demented adults with mild, early-stage PD were matched for years of education, age, and gender with a sample of healthy individuals. Participants completed a test battery assessing objective memory, subjective memory, and depressive symptoms, and an instrumental analysis of gait and functional mobility was performed. Participants with PD had poorer objective memory across all indices measured and displayed a restricted set of gait and posture impairments. Working memory performance was selectively related to gait and posture measures. Moreover, participants with PD had lower trust in their memory efficiency relative to the past than the control healthy group. Finally, 22% of the variance in seriousness of the consequences of forgetting was predicted by education and general cognitive efficiency. Overall, the present findings confirm the presence of changes in both objective and subjective memory in PD, independent from depressive symptoms.

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Gait, posture and cognition in Parkinson's disease

Cited by 32 publications

References 55 publications

Factors associated with the risk of falls in hospitalized adult patients

Factors associated with the risk of falls in hospitalized adult patients

Backward Gait is Associated with Motor Symptoms and Fear of Falling in Patients withDe NovoParkinson's Disease

Memory, subjective memory and motor functioning in non-demented elders with and without Parkinson’s disease

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