We have selected and analyzed a sample of OB stars with known line-of-sight velocities determined through ground-based observations and with trigonometric parallaxes and proper motions from the Gaia DR2 catalogue. Some of the stars in our sample have distance estimates made from calcium lines. A direct comparison with the trigonometric distance scale has shown that the calcium distance scale should be reduced by 13%. The following parameters of the Galactic rotation curve have been determined from 495 OB stars with relative parallax errors less than 30%: (U, V, W ) ⊙ = (8. 16, 11.19, 8.55)±(0.48, 0.56, 0.48) km s −1 , Ω 0 = 28.92 ± 0.39 km s −1 kpc −1 , Ω ′ 0 = −4.087 ± 0.083 km s −1 kpc −2 and Ω ′′ 0 = 0.703 ± 0.067 km s −1 kpc −3 , where the circular velocity of the local standard of rest is V 0 = 231 ± 5 km s −1 (for the adopted R 0 = 8.0 ± 0.15 kpc). The parameters of the Galactic spiral density wave have been found from the series of radial, V R , residual tangential, ∆V circ , and vertical, W, velocities of OB stars by applying a periodogram analysis. The amplitudes of the radial, tangential, and vertical velocity perturbations are f R = 7.1 ± 0.3 km s −1 , f θ = 6.5 ±0.4 km s −1 , and f W = 4.8 ±0.8 km s −1 , respectively; the perturbation wavelengths are λ R = 3.3±0.1 kpc, λ θ = 2.3±0.2 kpc, and λ W = 2.6±0.5 kpc; and the Sun's radial phase in the spiral density wave is (χ ⊙ ) R = −135±5 • , (χ ⊙ ) θ = −123±8 • , and (χ ⊙ ) W = −132±21 •