“…It was shown that 2 subjects showed extreme differences with the linear measurement results which had greater measurement results compared to the active contour Laplacian of Gaussian (LoG), this occurred in subjects with cystic ovarian neoplasms which had a tendency to malignancy (malignant) characterized by edge surfaces patchy, containing one or more complex mixtures Vol.2, No.11, October 2023 such as solid masses, hemorrhagic components, and septations. This is in line with research conducted by Hafidz (2020) which revealed that malignant ovarian tumors have cystic, mixed, solid, and ascitic components (Aryan et al, 2020). So it is recommended to measure the volume of cystic ovarian neoplasms with a tendency to malignancy using the active contour Laplacian of Gaussian (LoG) volume measurement technique because it has higher sensitivity, utilizing the reliability of edge detection to measure each slice containing clinical information following the shape and size according to surface conditions and the shape.…”