Gambaran Penggunaan Antibiotik di Bangsal Penyakit Dalam RSUD Bangil Kabupaten Pasuruan

Rachmawati, Sinta; Fazeri, Rizki Laili; Norcahyanti, Ika

doi:10.20961/jpscr.v5i1.35254

Cited by 5 publications

(5 citation statements)

References 3 publications

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“…There were 20 reports (5 193 626 patients) that reported data on antibiotic consumption, of which 16 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 in inpatients and four 34 , 35 , 36 , 37 in outpatients. Most of these studies were conducted in hospital settings (16 reports, 76.2%), in Java (14 reports, 66.7%), and between 2016-2021 (17 reports, 81.0%; Table S4).…”

Section: Resultsmentioning

confidence: 99%

Optimizing antibiotic use in Indonesia: A systematic review and evidence synthesis to inform opportunities for intervention

Limato

Lazarus

Dernison

et al. 2022

The Lancet Regional Health - Southeast Asia

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Section: Resultsmentioning

confidence: 99%

Optimizing antibiotic use in Indonesia: A systematic review and evidence synthesis to inform opportunities for intervention

Limato

Lazarus

Dernison

et al. 2022

The Lancet Regional Health - Southeast Asia

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“…The high frequency of use causes the compounding of ceftriaxone to be carried out in hospitals is also high. Ceftriaxone is an antibiotic that is often prescribed because it has a broad spectrum and is effective for the treatment of infections caused by gram-positive, negative and anaerobic bacteria (Rachmawati et al, 2020). In addition, Ceftriaxone also has a relatively cheap price and relatively less toxicity compared to other types of antibiotics (Ardyanti, 2016).…”

Section: Quantitative Methodsmentioning

confidence: 99%

Rationality of Antibiotics Use With Quantitative and Qualitative Methods at Hospital in Indonesia

Suminar

2022

COMORBID

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Infection is one of the biggest causes of death in Indonesia which can be influenced by the appropriate use of antibiotics. Irrational use of antibiotics can cause bacteria to become resistant to antibiotics so that the effectiveness of the drug decreases or even disappears. This study aims to evaluate the use of antibiotics given to inpatients at a private hospital in Indonesia both quantitatively and qualitatively in the period July to December 2021. This study is an observational study with retrospective data collection where qualitative analysis using the Gyssens Method and quantitative analysis uses the DDD method. The results of the qualitative analysis showed that from 30 cases observed, there were 9 cases (30%) irrational prescriptions, namely 1 case in category V, 4 cases in category IVA, 2 cases in category IIIB and 2 cases in category IIA. The results of the quantitative analysis showed that the antibiotics with the highest DDD/100 patient days in the period July to December 2021 were Ceftriaxone with a successive value of 39.15; 39.81; 36.22; 55.65; 41,48 and 49, 42 while antibiotics with the lowest DDD/100 patient-days values in the period July to December obtained different results. Based on research results, there are irrational antibiotic prescriptions and Ceftriaxone became the most commonly prescribed antibiotic.

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“…A total of 20 reports (5 193 626 patients) reported data on antibiotic consumption. [19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] Most of the studies were conducted in hospital settings (16 reports, 76.2%), in Java (14 reports, 66.7%), and between 2016-2021 (17 reports, 81.0%; Table S4). The pooled estimate of overall antibiotic…”

Section: Antibiotic Consumptionmentioning

confidence: 99%

Optimizing antibiotic use in Indonesia: a systematic review and synthesis of current evidence to inform opportunities for intervention

Limato

Lazarus

Dernison

et al. 2022

Preprint

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Introduction A major driver of antimicrobial resistance (AMR) and poor clinical outcomes is suboptimal antibiotic use, although data are lacking in low-resource settings. We reviewed studies on systemic antibiotic use (WHO ATC/DDD category J01) for human health in Indonesia, and synthesized available evidence to identify opportunities for intervention. Methods We systematically searched five international and national databases for eligible peer-reviewed articles, in English and Indonesian, published between 1 January 2000 and 1 June 2021 including: 1) antibiotic consumption; 2) prescribing appropriateness; 3) antimicrobial stewardship (AMS); 4) perceptions among consumers and providers. Two independent reviewers included studies and extracted data. Study-level data were summarized using random-effects model meta-analysis for consumption and prescribing appropriateness, effect direction analysis for AMS interventions, and qualitative synthesis for perception surveys. (PROSPERO CRD42019134641) Results Of 9323 search hits, we included 100 reports on antibiotic consumption (20), prescribing appropriateness (49), AMS (13), and/or perception (25) (8 categorized in >1 domain). The pooled estimate of overall antibiotic consumption was 110.1 DDD/100 patient-days (95%CI98.5-121.6), with ceftriaxone, ampicillin and levofloxacin being most consumed. Pooled estimates for overall appropriate prescribing (according to Gyssens method) were 33.5% (95%CI18.1-53.4%) in hospitals and 49.4% (95%CI23.7-75.4%) in primary care. Pooled estimates for appropriate prescribing (according to reference guidelines) were, in hospitals, 99.7% (95%CI97.4-100%) for indication, 84.9% (95%CI38.5-98.0%) for drug choice, and 6.1% (95%CI0.2-63.2%) for overall appropriateness, and, in primary care, 98.9% (95%CI60.9-100%) for indication, 82.6% (95%CI50.5%-95.7%) for drug choice and 10.5% (95%CI0.8-62.6%) for overall appropriateness. The few AMS intervention studies conducted to date suggested potential to reduce antibiotic consumption and improve prescribing appropriateness. Key themes identified in perception surveys were lack of antibiotic knowledge among consumers and non-prescription antibiotic self-medication. Conclusions Context-specific strategies are urgently needed to improve rational antibiotic use in Indonesian hospitals and communities, with critical evidence gaps concerning private and informal health providers.

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Gambaran Penggunaan Antibiotik di Bangsal Penyakit Dalam RSUD Bangil Kabupaten Pasuruan

Cited by 5 publications

References 3 publications

Optimizing antibiotic use in Indonesia: A systematic review and evidence synthesis to inform opportunities for intervention

Optimizing antibiotic use in Indonesia: A systematic review and evidence synthesis to inform opportunities for intervention

Rationality of Antibiotics Use With Quantitative and Qualitative Methods at Hospital in Indonesia

Optimizing antibiotic use in Indonesia: a systematic review and synthesis of current evidence to inform opportunities for intervention

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