Ganglioneuroma: computed tomography and magnetic resonance features

Ichikawa, Tomoaki; Ohtomo, Kuni; Araki, Tadashi; Fujimoto, Hajime; Nemoto, Kenji; Nanbu, Atsushi; Onoue, M; Aoki, Katsuhiko

doi:10.1259/0007-1285-69-818-114

Cited by 142 publications

(96 citation statements)

References 24 publications

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“…In one of our patients, however, calcification was dense and nodular. At enhanced CT, varying degrees of contrast enhancement have been described; Ichikawa et al (10), for example, reported delayed heterogeneous enhancement, and in our case, enhancement was delayed, septum-like and heterogeneous. Variations are explained by the presence in the tumors of an abundance of myxoid matrices, resulting in delayed and progressive accumulation of contrast material in extracellular space.…”

Section: Discussionsupporting

confidence: 50%

“…The tumors contain calcification in about 20% of cases (8), a feature which in childhood may help differentiate ganglioneuroma from neuroblastoma (3). In the latter, calcification is more often amorphous and of a rough pattern (3,9), while in ganglioneuromas it is usually discrete and punctate (8,10). In one of our patients, however, calcification was dense and nodular.…”

Section: Discussionmentioning

confidence: 54%

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Imaging Findings of Retroperitoneal Ganglioneuroma

Lee

Kim

et al. 2003

J Korean Radiol Soc

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Section: Discussionsupporting

confidence: 50%

Section: Discussionmentioning

confidence: 54%

Imaging Findings of Retroperitoneal Ganglioneuroma

Lee

Kim

et al. 2003

J Korean Radiol Soc

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“…Whirlpool sigh is the characteristics feature on T2W1 that means a few curved or linear hypointense signal region exists in surrounding extensive hyperintense signal region [12,13]. Pathologic morphology of ganglioneuroma is constitued by strip Schwann cell and tufted gangliocyte.…”

Section: Discussionmentioning

confidence: 99%

Adrenal Ganglioneuroma: A Rare Case Report and Literature Review

Bentao¹

2017

UNOAJ

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Submit Manuscript | http://medcraveonline.com hyperaldosteronism, hypertension and hypercortisolism. Further examination was taken in our hospital. The contrast-enhanced CT identified a quasi-circular nodular lesion in the right adrenal gland, measuring 6x6.5cm and displaying heterogeneous with mottling and spotty dense calcification on the edge of the mass. The margin of lesion was clear and presented 46 HU in plain scan and 68-113 HU in the enhancement. The tumor surrounded the right renal vein and part of postcava, but didn't narrow the vessels (Figure 1). All of functional laboratory evolution showed negative including blood testing for catecholamines (epinephrine and norepinephrine) and their metabolites (metanephrine in serum and VMA in a 24-hour urine sample), free cortisol and ACTH (adrenocorticotropic hormone) in serum and plasma testing for renin-angiotensin-aldosterone under recumbent and upright state. A laparoscopic right adrenalectomy was performed ( Figure 2) and postoperative pathology revealed a right ganglioneuroma. Immunohistochemistry showed S-100, CD56, Syn and CgA staining are positive (Figure 3 & 4). After one year follow-up, the patient has not had any local recurrence and distant metastasis. AbstractBackground: Adrenal ganglioneuroma is a rare sympathetic tumor which originated from adrenal medulla [1]. Multi slice spiral CT and 3d reconstruction have gradually been considered as one of the most important technical for discovery and identification of the incidentalomas. However, the accurate diagnosis of this tumor remains a challenge due to its nonspecific clinic and radiological performance. This report presents the clinic and radiological data for the infrequent tumor which should share some experience to facilitate the criteria for the diagnosis of adrenal ganglioneuroma.

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“…Punctate and coarse calcification could also be observed in certain cases in a disseminated sprinkled pattern, and administration of contrast media could lead to low or moderate enhancement. MRI is superior to CT in defining the intraspinal involvement; low intensity on T1-weighted images (T1WI), marked high intensity on T2-weighted images (T2WI) and gradual increasing enhancement on dynamic MR images are typical appearances of GN (19).…”

Section: Discussionmentioning

confidence: 99%

Multiple cervical ganglioneuroma: A case report and review of the literature

Ma¹,

Liu²,

Liu³

2012

Oncology Letters

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Abstract. Ganglioneuromas (GNs) arising from neural crest sympathogonia are rare benign neurogenic tumors. The most commonly affected sites are the posterior mediastinum, the retroperitoneum and the adrenal gland. GNs often present as a solitary, painless and slow-growing mass, and multiple occurrences in the cervical region are extremely rare. Here, we report a case of massive multiple cervical GN in a 4-year-old girl, and review cases of cervical GN that have been reported in the past 10 years. The results demonstrated that cervical GN, compared to other sites, is seldom secretory. The signs and symptoms of cervical GN are unspecific; the ultimate diagnosis of GN depends on pathological examination. Fine-needle aspiration biopsy has limited value in diagnosis. Surgical excision is the treatment of choice and the prognosis is excellent even in cases where complete excision cannot be achieved. Furthermore, GNs should be considered in patients with multiple masses in the neck.

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Ganglioneuroma: computed tomography and magnetic resonance features

Cited by 142 publications

References 24 publications

Imaging Findings of Retroperitoneal Ganglioneuroma

Imaging Findings of Retroperitoneal Ganglioneuroma

Adrenal Ganglioneuroma: A Rare Case Report and Literature Review

Multiple cervical ganglioneuroma: A case report and review of the literature

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