Ganglioneuromatous Polyposis Associated with Juvenile Polyps and a Tubular Adenoma

Rafiq, Shazia; Hameer, Hussein R.; Sitrin, Michael D.

doi:10.1007/s10620-005-2465-4

Cited by 11 publications

(12 citation statements)

References 9 publications

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“…Besides chronic diarrhea, one patient described abdominal soreness, cramping and distension as well. Rectal bleeding was only encountered in a 19-year-old woman, who had a solitary polypoidal rectal GN (2,3). Rectal bleeding in our patient may have been due to the adenomatous polyps or, alternatively, the GN.…”

Section: Discussionmentioning

confidence: 56%

“…They are mostly located in the posterior mediastinum, followed by the retroperitoneum (1,2). Involvement of the gastrointestinal (GI) tract is an extremely rare phenomenon, although cases have been reported throughout the GI tract, mainly in the appendix vermiformis, terminal ileum, stomach, and intestines (3,4). GNs localized in the GI tract usually present with abdominal pain, obstruction, constipation, ileus, appendicitis, and chronic diarrhea.…”

Section: Introductionmentioning

confidence: 99%

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Ganglioneuromatous polyposis of the colon in a patient with multiple adenomatous polyps

Arslan¹,

Ekız²,

Yılmaz³

et al. 2012

Turk J Gastroenterol

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Section: Discussionmentioning

confidence: 56%

Section: Introductionmentioning

confidence: 99%

Ganglioneuromatous polyposis of the colon in a patient with multiple adenomatous polyps

Arslan¹,

Ekız²,

Yılmaz³

et al. 2012

Turk J Gastroenterol

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“…Rarely, large GNs may cause symptoms of abdominal pain, constipation, obstruction, or bleeding secondary to the size and location within the colon. In general, solitary polypoid GNs are asymptomatic [6,7].…”

Section: Discussionmentioning

confidence: 99%

A case of ganglioneuroma of the colon during routine colonoscopy

Herman¹,

Abed²,

Shi³

et al. 2015

IJCRI

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International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. Case Report: A 57-year-old African-American male with a history of untreated chronic hepatitis C cirrhosis with viral load of over 4 million copies, seizure disorder, mild mental retardation, hypothyroidism, hypertension, diabetes mellitus type 2, presented to the gastroenterology clinic for scheduling of a screening colonoscopy. At that time, he was completely asymptomatic. On colonoscopy, one 4 mm sessile polyp was resected in the sigmoid colon and was histologically diagnosed as a ganglioneuroma (GN). IJCRI publishes Conclusion:The finding of an asymptomatic, solitary GN in our patient does not warrant more frequent colon cancer screening given its benign nature.

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“…Diffuse ganglioneuromatosis is a poorly demarcated nodular and diffuse intramural or transmural proliferation of ganglioneuromatous tissue elements involving the enteric plexuses. Transmural ganglioneuromatosis with the involvement of the myenteric plexus predominates in individuals with multiple endocrine neoplasia IIB (MEN IIB), whereas the involvement limited to the mucosa characterizes the disease in von Recklinghausen's disease [3]. Colonic adenocarcinoma has been described in association with diffuse ganglioneromatosis and ganglioneuromatous polyposis in a small number of cases [3].…”

Section: Discussionmentioning

confidence: 99%

“…Though they may be found anywhere in the body, particularly in the distribution of the major sympathetic ganglia, their involvement in the gastrointestinal tract is a rare occurrence. Some reports have indicated that ganglioneuromas of the gastrointestinal tract have been found in patients with several systemic disorders including multiple endocrine neoplasia IIB (MEN IIB), von Recklinghausen's disease, tuberous sclerosis, Cowden's disease, juvenile polyposis, filiform polyposis, and colonic adenocarcinoma [3,4]. …”

Section: Introductionmentioning

confidence: 99%