“…1,2 The aftereffects can range from long-term functional hand problems, paresthesia, heat/cold intolerance, the need for prolonged rehabilitation, and absence from work, 3 to long-lasting skin changes, 4 devastating skin and soft tissue loss, limb gangrene, and amputation. 5,6 Given the devastating consequences, even the lowest reported incidence merits an awareness of this possibility in personnel administering intravenous (IV) therapy as well as knowledge of the measures to alleviate its potentially disastrous effects.…”