Garcinia cambogia and diabetes mellitus: a lack of evidence?

Abstract

Diabetes Mellitus is a disease characterized by hyperglycemia resulting from defects in insulin secretion. Garcinia Cambogia is an Asian plant used commonly as nutritional supplement for weight loss.Objective: The purpose of this study is to perform a mini review about Garcinia Cambogia consumption and its relationship with DM condition in humans.Methods: Studies were searched in Pubmed, Web of Science and Scopus databases and 62 articles were identified and reviewed in an integrative method. After a criterial analysis, 3 articles were included on this mini review.Results: Two studies found that Garcinia Cambogia in association with Glucomannan had a positive association related to comorbidities as Diabetes Mellitus and its markers (glycemia, triglycerides, cholesterol). However, a case report showed an adverse effect on a high dose Garcinia Cambogia consumption. Conclusion:It is possible that Garcinia Cambogia consumption influences Diabetes Mellitus condition, although more studies are necessary for higher efficacy understanding.