Simulated Quantum Annealing (SQA) is a heuristic algorithm which can solve Quadratic Unconstrained Binary Optimization (QUBO) problems by emulating the exploration of the solution space done by a quantum annealer. It mimics the quantum superposition and tunnelling effects through a set of correlated replicas of the spins system representing the problem to be solved and performing Monte Carlo steps. However, the effectiveness of SQA over a classical algorithm strictly depends on the cost/energy profile of the target problem. In fact, quantum annealing only performs well in exploring functions with high and narrow peaks, while classical annealing is better in overcoming flat and wide energy-profile barriers. Unfortunately, real-world problems have a heterogeneous solution space and the probability of success of each solver depends on the size of the energy profile region compatible with its exploration mechanism. Therefore, significant advantages could be obtained by exploiting hybrid solvers, which combine SQA and classical algorithms. This work proposes four new quantum-classical algorithms: Simulated Quantum Parallel Tempering (SQPT), Simulated Quantum Population Annealing (SQPA), Simulated Quantum Parallel Tempering -Population Annealing v1 (SQPTPA1) and Simulated Quantum Parallel Tempering -Population Annealing v2 (SQPTPA2). They are obtained by combining SQA, Parallel Tempering (PT), and Population Annealing (PA). Their results are compared with those provided by SQA, considering benchmark QUBO problems, characterized by different profiles. Even though this work is preliminary, the obtained results are encouraging and prove hybrid solvers' potential in solving a generic optimization problem.