Gas Chromatographic-Mass Spectrometric Analysis of Volatiles Obtained by HS-SPME-GC-MS Technique from<i>Stachys lavandulifolia</i>and Evaluation for Biological Activity: A Review

Mohammadhosseini, Majid; Akbarzadeh, Abolfazl; Hashemi‐Moghaddam, Hamid

doi:10.1080/0972060x.2016.1221741

Cited by 18 publications

(6 citation statements)

References 91 publications

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“…The general details related to the DDA approach have been pointed out in Clinical Laboratory Standard Institute (CLSI) recommendations along with the report of Scorzoni et al . and some of our previous works . Concisely, antibacterial activity was determined by measurement of the diameter of the inhibition zone in millimeters, including the disc diameter, against the microorganisms.…”

Section: Methodsmentioning

confidence: 99%

Profiling of Compositions of Essential Oils and Volatiles of Salvia limbata Using Traditional and Advanced Techniques and Evaluation for Biological Activities of Their Extracts

Mohammadhosseini

Akbarzadeh

Flamini

2017

Chemistry & Biodiversity

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In the present work, the essential oils and volatiles from flowers, leaves, and stems of Salvia limbata obtained using microwave-assisted hydrodistillation, solvent-free microwave extraction, headspace-assisted analysis, and headspace-solid phase microextraction have been characterized for the first time. The results have been also compared with those from traditional separation techniques involving hydrodistillation and steam distillation. Regardless of some common compounds in all of the profiles, some dissimilarities were noted due to the use of different extracting approaches. Taking into account the chemical categories, sesquiterpene hydrocarbons were found as the most represented group of natural compounds contributing to the chemical profiles. It was also noted that the methanol extracts obtained from the flowers of Sal. limbata showed a desirable antioxidant activity, comparable to the standard antioxidant butylated hydroxytoluene. Furthermore, using the disc diffusion and broth microdilution methods, all the tested bacteria demonstrated weak to moderate and moderate to strong sensibilities to the MeOH extracts obtained from different plant parts of Sal. limbata.

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Section: Methodsmentioning

confidence: 99%

Profiling of Compositions of Essential Oils and Volatiles of Salvia limbata Using Traditional and Advanced Techniques and Evaluation for Biological Activities of Their Extracts

Mohammadhosseini

Akbarzadeh

Flamini

2017

Chemistry & Biodiversity

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“…The plant is known as Chay-e-kouhi in Persian, whereas in English it is called Betony. Also, its common names include heal-all, self-heal, woundwort, betony, lamb's ears, and hedge nettle [ 134 ].…”

Section: Species Of the Lamiaceae Family With Potential Analgesic/mentioning

confidence: 99%

Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review

Uritu

Mihai

Stanciu

et al. 2018

Pain Research and Management

268

143

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Recently, numerous side effects of synthetic drugs have lead to using medicinal plants as a reliable source of new therapy. Pain is a global public health problem with a high impact on life quality and a huge economic implication, becoming one of the most important enemies in modern medicine. The medicinal use of plants as analgesic or antinociceptive drugs in traditional therapy is estimated to be about 80% of the world population. The Lamiaceae family, one of the most important herbal families, incorporates a wide variety of plants with biological and medical applications. In this study, the analgesic activity, possible active compounds of Lamiaceae genus, and also the possible mechanism of actions of these plants are presented. The data highlighted in this review paper provide valuable scientific information for the specific implications of Lamiaceae plants in pain modulation that might be used for isolation of potentially active compounds from some of these medicinal plants in future and formulation of commercial therapeutic agents.

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“…This simultaneous effect might be partially described by the signal amplification on GABAA receptor. Moreover, SL extract has active components such as phenylethanoid, terpenoid, and flavonoid with biological functions (Mohammadhosseini, Akbarzadeh, & Hashemi-Moghaddam, 2016;Monji et al, 2011;Neshat et al, 2017). Flavonoids are an important category of natural antioxidant components (Hajhashemi et al, 2007) with several neuro-pharmacologic features.…”

Section: Discussionmentioning

confidence: 99%

Effect of Hydroalcoholic Extract of Stachys lavandulifolia on Pentylenetetrazole-induced Seizures in Male Mice: The Role of GABAergic and Opioidergic Systems

Behzadnia

Naseri

Emamhadi

et al. 2022

BCN

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Introduction: Epilepsy is one of the most common neurological disorders. Though there are effective medications available for treatment of epilepsy, the use of most drugs is associated with many side effects and drug interactions. Stachys lavandulifolia (SL) used in Iranian traditional medicine show anti-anxiety and sedative actions. The objective of the current study was to evaluate the anticonvulsant effect of hydroalcoholic extract of SL on the pentylenetetrazole (PTZ)-induced seizure in male mice and the role of benzodiazepine and opioid receptors. Methods: This study was conducted on 100 male mice randomly categorized into 10 groups: Normal Saline, Diazepam groups (0.025 and 0.1 mg/kg), SL extract groups (50, 100 and 200 mg/kg), Diazepam 0.025 mg/kg + SL extract 50mg/kg and three groups that pre-treated with NS, Flumazenil or Naloxone, 5 min before injection of 200 mg/kg extract. After 30 min, PTZ (80 mg/kg) was injected to animals and seizure indices were evaluated. Results: The SL extract attenuated the PTZ-induced seizures in a dose dependent manner and pre-treatment with flumazenil reversed this effect of SL extract but pre-treatment with naloxone could not reverse this effect, because seizure indices on naloxone pretreated group was still lower than normal saline group. Combination of ineffective dose of diazepam and SL extract decrease PTZ-induced seizures. Discussion: The results of our study showed the anticonvulsant properties of hydroalcoholic extract of SL. These effects might be due to the impact of the components of this extract on the central benzodiazepine system.

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Gas Chromatographic-Mass Spectrometric Analysis of Volatiles Obtained by HS-SPME-GC-MS Technique fromStachys lavandulifoliaand Evaluation for Biological Activity: A Review

Cited by 18 publications

References 91 publications

Profiling of Compositions of Essential Oils and Volatiles of Salvia limbata Using Traditional and Advanced Techniques and Evaluation for Biological Activities of Their Extracts

Profiling of Compositions of Essential Oils and Volatiles of Salvia limbata Using Traditional and Advanced Techniques and Evaluation for Biological Activities of Their Extracts

Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review

Effect of Hydroalcoholic Extract of Stachys lavandulifolia on Pentylenetetrazole-induced Seizures in Male Mice: The Role of GABAergic and Opioidergic Systems

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