Gas chromatography/ion trap tandem mass spectrometry for the analysis of halobenzenes in soils by solid-phase microextraction

Abstract

Headspace solid‐phase microextraction combined with gas chromatography/ion trap tandem mass spectrometry (HS‐SPME/GC/ITMS/MS) was used for the analysis of 12 halobenzenes from soil samples. For MS/MS optimisation, the experiments were performed by precursor ion selection and software controlled operations. Collision‐induced dissociation (CID) can be achieved by two different approaches, resonant and non‐resonant excitation modes. Different results were obtained using the two approaches, and the resonant excitation mode was chosen as the best for all halobenzenes. Parameters such as the CID excitation amplitude, excitation RF storage level and CID bandwidth frequency were optimised to maximise the formation of halobenzene product ions. A 100‐µm polydimethylsiloxane fibre was used for the isolation and preconcentration of the analytes. The HS‐SPME/GC/ITMS/MS method was applied to the analysis of halobenzenes in an agricultural soil sample. The halobenzenes were quantified by standard addition, which led to good reproducibility (RSD between 4.7 and 9.2%) and detection limits in the low pg/g range. The method was validated by comparing the results with those obtained in a European inter‐laboratory exercise. Copyright © 2000 John Wiley & Sons, Ltd.

Determination of benzene series compounds and chlorobenzenes in water sample by static headspace gas chromatography with flame ionization detection

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Homogeneous liquid-phase microextraction followed by filtration-based phase separation coupled to high-performance liquid chromatography

“…Among persistent organic pollutants, chlorobenzenes (CBs) are some of the most frequently encountered compounds in aqueous systems. These compounds enter the environment via natural and anthropogenic sources, and are ubiquitous due to their extensive use over the past several decades . CBs are hazardous to health and have been ranked as priority pollutants by the U.S. Environmental Protection Agency (EPA) .…”

Determination of chlorobenzenes in pure, tap, and sea water by static headspace gas chromatography‐electron capture detection

“…Chlorobenzenes (CBs), which have been extensively used in chemical synthesis of pesticides, pharmaceuticals, dyes, plastics, and other chemical products for several decades, are ubiquitously distributed in the aquatic environment as a result of uncontrolled release of effluents and industrial atmospheric discharges . As CBs are lipophilic compounds, chemically stable in nature, resistant to degradation, and can cause liver and renal cancer in mammals , they have been ranked as priority pollutants by the US Environmental Protection Agency (EPA) .…”