Introduction: Ajwain (Trachyspermum ammi L.) seeds are derived from a herb plant of the family Apiaceae. It is also known as Ajowan caraway, bishops weed or carom and has substantial medicinal properties. Methods: The keywords of Ajwain, traditional medicine, health benefits, pharmaceutical science and health benefits were searched in Google Scholar, Scopus, ResearchGate and PubMed. Results: Ajwain oil has a wide range of medicinal applications, such as antibacterial, antifungal, antiinflammatory, antioxidant, antibacterial, cytotoxic, antilithiasis, nematicidal, anthelmintic, and antifilarial activities. The seeds have stimulant, sialagogue, stomachic, carminative, aromatic, antiseptic, antihypertensive, antispasmodic, antiparasitic, anthihistamine, antiscorbutic, vermicide, emmenagogue, digestive and antiseptive properties. Conclusion: Ajwain is one of the most important medicinal plants and can promote good health and serve as a nutrition therapy on the basis of traditional Asian medicine.