Gas holdup, foaming and oxygen transfer in a jet loop bioreactor with artificial foaming media and yeast culture

Flores-Cotera, Luis B.; García-Salas, Sergio

doi:10.1016/j.jbiotec.2004.12.011

Cited by 11 publications

(3 citation statements)

References 22 publications

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“…[11][12][13][14] 14 Finally, only a few studies have evaluated the jet-loop hydrodynamics under microorganism culture conditions, such as viscosity and ionic strength of a culture medium, 18,20 or in the presence of microorganisms. 20,25 The high mass transfer and mixing efficiency justify the potential use of the jet-loop reactor in a complex oil-water-air system for the biotechnological production of biomolecules of industrial interest. Therefore, this work aims to present an analysis of the main operating conditions of a typical stirred tank reactor, an airlift reactor, and a jet-loop reactor equipped with a Venturi tube injector in the presence of 1%, 2%, and 5% v/v of avocado oil.…”

Section: Introductionmentioning

confidence: 99%

“…It has been mainly used for the removal of pollutants (such as methanol) from the air, 20 the treatment of brewery and winery wastewater, 21‐23 phenol bioremoval, 24 and the treatment of agro‐industrial effluents 11‐14 . Finally, only a few studies have evaluated the jet‐loop hydrodynamics under microorganism culture conditions, such as viscosity and ionic strength of a culture medium, 18,20 or in the presence of microorganisms 20,25 …”

Section: Introductionmentioning

confidence: 99%

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Intensification of multiphase systems with a jet‐loop reactor: characterization of mass transfer, mixing time, drop oil size, and biomass growth

Bourguett‐Rosas,

Arenas‐García,

Vergara‐Porras

et al. 2024

J of Chemical Tech & Biotech

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BACKGROUNDThe development of processes for transforming vegetable oils into useful products has received increasing attention in the biotechnological field. The reactor used for this purpose should meet adequate mass transfer, mixing and oil dispersion conditions. In this work comprehensive research into the use of a jet‐loop reactor as a potential alternative to airlift and stirred tank reactors was conducted in presence of avocado oil in a water‐air system. Additionally, the assessment of the jet‐loop for biomass growth in presence of oil was performed.RESULTSThe increase of avocado oil from 1 to 5 % v/v resulted in a reduction in the performance of the three reactors. Despite the airlift reactor having the lowest power input, it exhibited the worst performance in terms of mass transfer, mixing and oil dispersion. The estimation of the energetic oxygen transfer efficiency (Kg O2 KW‐1 h‐1) allowed the determination that the jet‐loop reactor was superior to the stirred tank. This superiority was attributed to the low values of the mixing time and oil droplet diameter observed in the jet‐loop reactor. Finally, all these parameters had a positive impact on the growth of Wautersia eutropha in the jet‐loop reactor compared with the other two reactors.CONCLUSIONSThe results showed that the jet‐loop reactor presented superior performance in most cases compared to the stirred tank and airlift reactors. Particularly, the jet‐loop exhibits an interesting potential to reduce the size of the avocado oil droplets, which could lead to a significative increase in the growth rate of Wautersia eutropha.This article is protected by copyright. All rights reserved.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Intensification of multiphase systems with a jet‐loop reactor: characterization of mass transfer, mixing time, drop oil size, and biomass growth

Bourguett‐Rosas,

Arenas‐García,

Vergara‐Porras

et al. 2024

J of Chemical Tech & Biotech

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“…Over the last decades several attempts have been made to apply JLR principles in fermentation processes . Although the general applicability was shown, their commercial application in biotechnological production processes as mentioned above has not been realized yet or was not reported in literature.…”

Section: Introductionmentioning

confidence: 99%

Jet aeration as alternative to overcome mass transfer limitation of stirred bioreactors

Weber

Schaepe

Freyer

et al. 2018

Engineering in Life Sciences

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In industrial biotechnology increasing reactor volumes have the potential to reduce production costs. Whenever the achievable space time yield is determined by the mass transfer performance of the reactor, energy efficiency plays an important role to meet the requirements regarding low investment and operating costs. Based on theoretical calculations, compared to bubble column, airlift reactor, and aerated stirred tank, the jet loop reactor shows the potential for an enhanced energetic efficiency at high mass transfer rates. Interestingly, its technical application in standard biotechnological production processes has not yet been realized. Compared to a stirred tank reactor powered by Rushton turbines, maximum oxygen transfer rates about 200% higher were achieved in a jet loop reactor at identical power input in a fed batch fermentation process. Moreover, a model‐based analysis of yield coefficients and growth kinetics showed that E. coli can be cultivated in jet loop reactors without significant differences in biomass growth. Based on an aerobic fermentation process, the assessment of energetic oxygen transfer efficiency [kgO2 kW−1 h−1] for a jet loop reactor yielded an improvement of almost 100%. The jet loop reactor could be operated at mass transfer rates 67% higher compared to a stirred tank. Thus, an increase of 40% in maximum space time yield [kg m−3 h−1] could be observed.

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Foam Formation and Control in Bioreactors

Delvigne¹,

Lecomte²

2010

Encyclopedia of Industrial Biotechnology

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The generation of foam during the course of a bioprocess remains a major technological challenge to be resolved and needs further investigation. The foaming tendency of the cultivation media used in bioreactors induces various direct,that is microbial cells stripping and contamination, as well as indirect adverse effects, that is modification of the properties of the medium subsequent to the addition of chemical antifoam leading to toxic effects at the level of the microbial metabolism and fouling of the downstream processing equipment. In this work, the mechanisms leading to foam formation are described at the molecular level (adsorption of surface‐active molecule at the gas–liquid interface), and also at the process level. In view of the potential foam‐associated problems, special attention is given to the level of the compatibility of the intensification of the gas–liquid operation in bioreactors. Due to these considerations, both the chemical and mechanical antifoam techniques have been evolved. Numerous new antifoam formulations and original combinations of chemical antifoams have been especially designed in order to meet the specific requirements of bioprocesses. Original mechanical techniques to prevent foam formation in bioreactors have been elaborated from combined knowledge involving the fluid dynamics of gas–liquid dispersion and interfacial processes (e.g. the “stirring as foam disruption” concept).

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Gas holdup, foaming and oxygen transfer in a jet loop bioreactor with artificial foaming media and yeast culture

Cited by 11 publications

References 22 publications

Intensification of multiphase systems with a jet‐loop reactor: characterization of mass transfer, mixing time, drop oil size, and biomass growth

Intensification of multiphase systems with a jet‐loop reactor: characterization of mass transfer, mixing time, drop oil size, and biomass growth

Jet aeration as alternative to overcome mass transfer limitation of stirred bioreactors

Foam Formation and Control in Bioreactors

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