Gas-Liquid Chromatographic Determination of Lincomycin

Synthesis and Bioactivity of Lincomycin 2-Monoesters

“…GC was conducted after conversion of the lincomycin 2-acyl esters to the corresponding 3,4,7-rris-O-trimethylsilyl ethers, as described by Houtman et al (5). A 1% solution of the ester in pyridine containing 20 % hexamethyldisilazane and 20% trimethylchlorosilane was used to give the silyl ethers.…”

Electrochemiluminescence detection with integrated indium tin oxide electrode on electrophoretic microchip for direct bioanalysis of lincomycin in the urine

“…2. (1) and 100 M clindamycin phosphate (2). The distance between the separation channel and the electrode was 40 m. Other conditions were the same as those in Fig.…”

“…It is effective primarily against Gram-positive pathogens. Lincomycin has been used in various illnesses, including the mouth and upper respiratory tract infections, as well as skin infections [1,2].…”

Study on the interaction between palladium(II)–lincomycin chelate and erythosine by absorption, fluorescence and resonance Rayleigh scattering spectra and its analytical applications

“…If Ery were not enough, the reaction would be incomplete. If Ery were excessive, ΔI would decrease because of the formation of Ery dimers by self-aggregation, which is unfavourable to the (1)(2)(3)(4)(5)(6) , 2.1, 1.8, 1.5, 1.2, 0.9, 0.6 μg/mL; (Linco) (7,8) ion-association reaction. Hence, 1.6 × 10 -5 mol/L was chosen as a suitable Ery concentration.…”

“…As a well-established drug used in human and veterinary medicine, it is mainly active against Gram-positive bacteria and has been applied in the treatment of various illnesses, including mouth and upper respiratory tract infections and skin infections (2,3). Various methods have been described in the literature for the analysis of Linco, such as microbiological assay (4), thin layer chromatography (TLC) (5), gas chromatography (6), highperformance liquid chromatography (HPLC) (7)(8)(9)(10)(11), liquid chromatography-mass spectrometry (LC-MS) (12)(13)(14)(15), electrochemistry (16)(17)(18), capillary electrophoresis (CE) (19,20), atomic absorption spectrometry (21) and spectrophotometry (SP) (21)(22)(23)(24)(25).…”