Gastric Disorders in the Services

Abstract

SULFHAPYRIDINE FOR CEREBROSPINAL FEVER M THE BRiTisH MEIDICAL JOURNAL epidemics should be treated with sulphapyridine in combination with either serum or antitoxin for further trial. Dosage with sulphapyridine may be increased with impLunity in subsequent trials and with the likelihood of improving results still fturther. Summary One hundred and sixty cases of cerebrospinal fever were treated in fouir groups: serum (50 cases), sulphapyridine (50 cases), sulphapyridine plus serum (30 cases), sulphapyridine plus antitoxin (30 cases). Satisfactory resLtIs were obtained, fatality rates for the groups being 38, 32, 26.6, and 20 per cent. respectively. The recovery rate was accelerated in the groups where sulphapyridine was emvloyedl. Blood cultUres were performed in 126 cases only; positive cultures were obtained in 100 cases, twenty-one of which ended fatally. Concentration of sulphapyridine in the cerebrospinal fluid was estimated, but the concentration appeared to have little if any relation to the dosage. No toxic reactions were experienced in any of the cases treated with sulphapyridine. We wish to thank Messrs. May and Baker for their courtesy in supplying sulphapyridine (M & B 693) free of charge for this test upon request. We also wish to thank the staff of the hospitals and laboratories, especially Dr. K. W. J. Lieu, for their cooperation. We are indebted to Mr. L. H. Barton for the estimations and also to Mr. Fanthorpe.

Alimentary-Tract Disturbances Secondary to Emotional or Physical Trauma

“…3 The incidence of ulcer in the British Expeditionary Force was in sharp contrast to figures obtained in the last war, where indigestion, inflammation and ulcers of the stomach were in a position somewhere between ninth and twelfth places in numerical importance. That this increase in gastrointestinal disturbances was not limited to the military services was evidenced by Willcox,4 who noted a striking incidence of digestive disorders in 1939 in London bus drivers. An the Polish campaign, while under the excitement and external emotional explosions incident to actual combat.…”

Contributo allo Studio delle Basi Genetiche dell'Ulcera Duodenale

“…Non sono mancate nel passato pubblicazioni sugli aspetti ereditari dell'ulcera peptica in generale o gastrica e duodenale in particolare. Alcune riportano genealogie nelle quali la malattia si ripete in vari soggetti (Helweg-Larsen, 1947;Levrat, Larbre e Richard, 1954;Wright, Grant e Jennings, 1955); altre rilevano la concordanza in coppie gemellari monozigotiche e dizigotiche (Freeman, 1947;Doig, 1957;Pilot, Lenkoski, Spiro e Schafer, 1957;Von Verschuer, 1959); altre infine riferiscono i risultati di ricerche sulla differenza di incidenza dell'ulcera tra i parenti prossimi di un caso indice e in famiglie controllo (Willcox, 1940;Nicol, 1941;Sallstrom, 1945;Bauer, 1950), o nella popolazione generale (Levin e Kuchur, 1936;Doll e Buch, 1950; Doll e Kelloch, 1951).…”