Gastric electrical stimulation for children with intractable nausea and gastroparesis

Islam, Saleem; Vick, Laura R.; Runnels, Matthew J.; Gosche, John R.; Abell, Thomas L.

doi:10.1016/j.jpedsurg.2007.10.005

Cited by 48 publications

(32 citation statements)

References 19 publications

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“…Currently, there is an increasing international interest in treating children and adolescents with GES [12,22]. As there are no established indications for GES in children, it is of great importance to find ways to select responders to the treatment.…”

Section: Discussionmentioning

confidence: 99%

“…[7]. This approach can also be applied in children [12]. However, in this study, previous surgical interventions in combination with the patients' young age made open surgery the preferred surgical technique.…”

Section: Surgical Techniquementioning

confidence: 90%

“…Islam et al [12] have reported positive results of GES in children and adolescents. In their study, the patients' mean age was 14 years; and the youngest child was 8 years old.…”

mentioning

confidence: 98%

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Temporary percutaneous and permanent gastric electrical stimulation in children younger than 3 years with chronic vomiting

Elfvin

Göthberg

Lönroth

et al. 2011

Journal of Pediatric Surgery

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Section: Discussionmentioning

confidence: 99%

Section: Surgical Techniquementioning

confidence: 90%

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Temporary percutaneous and permanent gastric electrical stimulation in children younger than 3 years with chronic vomiting

Elfvin

Göthberg

Lönroth

et al. 2011

Journal of Pediatric Surgery

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“…This stimulator produces at its lowest setting an electric pulse train with a frequency of 14 Hz and a current output of 5 mA, effectively decreases the symptoms of GP, and has a variable effect on gastric emptying. 1,6–9 …”

Section: Introductionmentioning

confidence: 99%

An endoscopic wireless gastrostimulator (with video)

Deb¹,

Tang²,

Abell³

et al. 2012

Gastrointestinal Endoscopy

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Background Gastric electric stimulation (GES) at a high-frequency, low-energy setting is an option for treating refractory gastroparesis. The currently available commercial stimulator, the Enterra neurostimulator (Medtronic Inc, Minneapolis, MN), however, requires surgical implantation and is powered by a nonrechargeable battery. Objective To develop and test a miniature wireless GES device for endoscopic implantation in an experimental model. Design In-vivo gastric signals were recorded and measured in a nonsurvival swine model (n = 2; 110-lb animals). Intervention An endoscopically placed, wireless GES device was inserted into the stomach through an overtube; the two GES electrodes were endoscopically attached to the gastric mucosa and secured with endoclips to permit stimulation. Main Outcome Measurements Stable electrogastrogram measures were observed during GES stimulation. Results Electrogastrogram recordings demonstrated that gastric slow waves became more regular and of constant amplitudes when stomach tissues were stimulated, in comparison with no stimulation. The frequency-to-amplitude ratio also changed significantly with stimulation. Limitation Nonsurvival pig studies. Conclusion Gastric electric stimulation is feasible by our endoscopically implanted, wireless GES device.

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“…11 A recent case series reports 9 patients aged 8 to 17 years who after having symptoms from 6 months to 2 years underwent gastric electrical stimulation placement. 12 Interestingly, patients had improvement in symptoms but continued to have abnormal gastric emptying values. The mechanism of gastric electrical stimulation is not fully understood; however, it may reduce sensory sensitivity.…”

Section: Gastric Electrical Stimulation In Pediatricsmentioning

confidence: 99%