Gastric Emptying and Small‐bowel Transit Rate in the Elderly

Abstract

Gastric emptying of liquid and small bowel transit in a group of elderly patients (mean age 79 years) was studied, with the elderly subjects compared to two groups of young controls. In 14 elderly patients, the initial rate of gastric emptying was significantly higher than in 14 young controls: the five-minute volume was 159 +/- 30 ml (mean +/- SEM) in the elderly patients and 294 +/- 22 ml in the young controls (p less than 0.005). The two groups' gastric emptying rates after five minutes were not significantly different. Small-bowel transit in 15 elderly patients was not significantly different from that found in 15 younger volunteers. These results suggest that gastric homeostatic mechanisms are impaired in the elderly.

Influence of Aging and Menopause on Postprandial Lipoprotein Responses in Healthy Adult Women

“…It has been shown that the rate of gastric emptying of liquids and solids decreases with age 29) ; however, intestinal motility is not altered and pancreatic secretion slightly decreases with age 30) . In addition, LPL activity has been reported to decrease with age 31) .…”

Postprandial plasma retinyl ester response is greater in older subjects compared with younger subjects. Evidence for delayed plasma clearance of intestinal lipoproteins.

“…Finally, to investigate the process of postprandial plasma retinyl ester clearance, we infused retinyl ester-rich plasma to a selected group of young adult and elderly subjects and determined the subsequent rate ofplasma retinyl ester decay. These 52 2/2 * Taken from 14-h overnight fasting blood. $ Decay curves were constructed as described in Fig.…”

“…time was unaltered by increasing age (50)(51)(52) The absorption of vitamin A in oral dose or feeding studies also depends on the resistance of the diffusion barrier at the intestinal cell surface. Hollander and Morgan (58) have shown in rats that the rate of uptake of radiolabeled vitamin A by perfused intestinal segments increases with advancing age, and have suggested that this finding is due to an age-related decrease in the resistance of the diffusion barrier at the intestinal cell surface.…”

Lipemia pós-prandial: influência do envelhecimento

“…Some studies have shown that the gastric emptying of liquids and solids decreases with age 10 , but intestinal motility is not altered with age 11 . Pancreatic secretion slightly decreases with age 12 .…”