Gastric neobladder: an experimental study in dog

Seif, M. M.; Aimen, M. S.; Kamel, H. H.

doi:10.21608/jvmr.2007.77912

Cited by 2 publications

(1 citation statement)

References 38 publications

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“…Augmentation cystoplasty is a commonly used for surgical procedure in order to increasing urinary bladder capacity for the reduction of high intra bladder pressure in patients with low urinary bladder capacity and for protection of the upper urinary tract (12). In the augmentation of the urinary bladder, the small and large bowel segments are widely used in different configurations (21). As an alternative to augmentation cystoplasty, intravesical pressure-reducing autoaugmentation may be performed.…”

Section: Introductionmentioning

confidence: 99%

Use of Fascia Lata Autograft for Augmentation of Bladder in Rabbits

Yönez¹

2018

Erciyes Üniversitesi Veteriner Fakültesi Dergisi

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In the present study; experimental defects were created in the rabbits at the urinary bladder and the repair of the defects with autogenous Fascia latae (FL) graft was provided. The aim was to evaluate whether the grafted urinary bladder capacity reached to the normal urinary bladder capacity. A total of 32, healthy male adult New Zealand rabbits were used in this study. The rabbits were randomly divided into four equal groups, i.e. group I, II, III and IV (control) according to the duration of euthanasia. Bladder capacities of the rabbits were measured preoperatively. Experimentally 2x2 cm defects were induced in the urinary bladder of the rabbits and repaired with autogenous FL graft in the first three groups. The rabbits in the control group underwent no surgical application. Postoperative bladder capacities of rabbits in the groups were measured at the end of 4 th (group I), 8 th (group II) and 12 th (group III and IV), weeks before being euthanized. The urinary bladder capacities of control group were compared with those of the rabbits in the other groups. As a result, it was concluded that the autogenous Fascia latae graft might be used successfully in the urinary bladder with decreased capacity.

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Section: Introductionmentioning

confidence: 99%

Use of Fascia Lata Autograft for Augmentation of Bladder in Rabbits

Yönez¹

2018

Erciyes Üniversitesi Veteriner Fakültesi Dergisi

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Full-Thickness Hysterocystoplasty for Management of a Large Bladder Defect: Experimental Study in Goats

Abdelrhman

Seddek

Bakr

et al. 2013

The Journal of Veterinary Medical Science

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ABSTRAcT. The uterine tissue of three healthy nonpregnant goats was evaluated experimentally as a graft for closure of a bladder defect. Goats were subjected to ovariectomy, and then one detubularized uterine horn was used as a graft to close a large defect in the ventral aspect of the bladder. Follow up included monthly radiographic and ultrasonographic examinations and evaluations of kidney function and electrolytes changes for six months. The goats were euthanized after six months, and both the bladder and the graft were examined macroscopically and histologically. The technique required less invasive procedures than those described with alternative techniques of cystoplasty, achieved a high survival rate without life-threatening complications post surgery, was associated with no significant changes in kidney function and electrolytes levels, showed proper healing of the transplanted graft by regeneration rather than repair without scaring or fibrosis and with complete covering of the graft by a healthy urothelium and was associated with no malignant transformation. Hysterocystoplasty is a noninvasive, non-life-threatening technique due to the close position of the bladder to the uterus, and proper healing of the graft reflects absence of pressure on its blood supply. It is an acceptable alternative technique for closure of a large bladder defect and avoids disadvantages of alternative techniques of cystoplasty. It might be accepted by owners of pets, and further studies in clinical cases of dogs are advised. Although cystoplasty is a historic topic that has been discussed well in scientific literature and argued at legendary proportion among urologists, the search for an ideal organ to replace a diseased bladder remains elusive for reconstructive urologists [32]. Many augmentation cystoplasty or neobladder techniques have been used routinely for treatment of reduced bladder compliance and capacity secondary to bladder infection and inflammation [27], neurogenic dysfunction or congenital bladder disorders [16], detrusor over activity [10], large bladder defects [8,9], bladder necrosis [30] and bladder tumors [7,12]. Although encouraging animal and human results have been reported with different techniques, each technique had its own limitations, complications and disadvantages [2,4,11,27].The ileum and colon have been used for decades for reconstruction of the bladder, in spite of the harmful contact of urine with the mucosa of the augmenting patch [23], which is predisposed to multiple short-and/or long-term complications like chronic bacteriuria or mucous secretion [1,23], stone formation [1,11,29], disturbance of calciumphosphate metabolism with potential bone growth retardation [24,28], altered hepatic and electrolyte metabolism [24], gastrointestinal motility disorders [23], augmenting patch perforation [1,6] and malignant transformation of the augmenting patch [1,14].Gastrocystoplasty has been described as an alternative technique; unfortunately, as the popularity of gastrocystoplasty increased, so did ...

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Gastric neobladder: an experimental study in dog

Cited by 2 publications

References 38 publications

Use of Fascia Lata Autograft for Augmentation of Bladder in Rabbits

Use of Fascia Lata Autograft for Augmentation of Bladder in Rabbits

Full-Thickness Hysterocystoplasty for Management of a Large Bladder Defect: Experimental Study in Goats

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