Gastric Pseudolymphomas Resembling Angioproliferative Lymph Node Hyperplasia

Toth, John P.; Rónay, P

doi:10.1159/000224962

Cited by 9 publications

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…13,15 Three other cases that were reported as gastric pseudolymphomas also could be considered as Castleman_s disease based on the reported pathologic findings. 16,17 HV-type Castleman_s disease mimicking sigmoid colon was reported, but its origin was mesentery of the sigmoid colon. 18 Thus, in total, five cases of Castleman_s disease of the stomach have been reported (Table 1).…”

Section: Discussionmentioning

confidence: 99%

Castleman's Disease of the Rectum: Report of a Case

Hata¹,

Ikeda²,

Ikenaga³

et al. 2007

Diseases of the Colon &Amp; Rectum

View full text Add to dashboard Cite

Gastrointestinal Castleman's disease is very rare. We report the case of a 52-year-old patient with asymptomatic rectal polyp, which was diagnosed as Castleman's disease. The rectal polyp was identified during preoperative workup of gastric adenocarcinoma. The rectal polyp was 4-cm long with a short, thick stalk. Pathologic examination of the resected polyp showed lymph follicle hyperplasia with remarkable lymphocyte and plasma cell infiltration in the submucosal area, consistent with plasma cell type of Castleman's disease. This is the first report of Castleman's disease of the rectum concomitant with gastric adenocarcinoma. A literature review of Castleman's disease identified only five cases of gastrointestinal Castleman's disease, and all five cases were of the hyaline vascular type. A high index of suspicion of this disease is important for preoperative diagnosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Castleman's Disease of the Rectum: Report of a Case

Hata¹,

Ikeda²,

Ikenaga³

et al. 2007

Diseases of the Colon &Amp; Rectum

View full text Add to dashboard Cite

show abstract

Gastric pseudolymphoma: Its three subtypes and relation to lymphoma

Brooks

Enterline

1983

Cancer

View full text Add to dashboard Cite

Three separate histologic types of gastric pseudolymphoma (GPL) are described: (1) the common “inflammatory” type usually accompanied by ulceration and extensive fibrosis; (2) the entity known as “nodular lymphoid hyperplasia,” which was associated with multiple intestinal lesions; and (3) the third reported case of angiofollicular lymphoid hyperplasia of the stomach (one with nodal involvement). Criteria for the common type were developed and, in general, confirm previous studies. However, the importance of evaluating nuclear cytology and mitotic rate are stressed. Organ infiltration by chronic lymphocytic leukemia should be excluded by the absence of an absolute peripheral lymphocytosis. In addition to the ten cases presented, the literature on 175 previous cases is summarized. GPL is estimated to account for 10‐15% of all gastric lymphoid tumors. In comparison to gastric lymphoma, GPL is usually smaller in size and occurs a decade earlier on the average. Since an associated focal lymphoma was documented in an additional five cases, this study proposes that pseudolymphoma be considered a precursor lesion with malignant potential. Extensive pathologic sampling and total surgical excision are recommended.

show abstract

Pseudolymphoma of the stomach. A clinicopathologic study of 15 cases

Tokunaga

Watanabe

Morimatsu

1987

Cancer

View full text Add to dashboard Cite

Fifteen cases of gastric pseudolymphoma (GPL) were studied and classified into three subtypes: The nodular type, which is elevated, representing a submucosal tumor. Histologically, the tumor is composed of lymphoid hyperplasia with no associated ulcer. The lesion is well demarcated with no sinusoidal structure. Those findings indicate a nonreactive state. The ulcerative type, which usually is accompanied by deep ulceration with extensive fibrosis. The erosive type, which is infiltrated by extensive lymphoid hyperplasia in the propria mucosa and submucosa. The latter two types represent the reactive state in response to chronic gastric ulcer or inflammation. One of four ulcerative GPLs, however, was associated with focal malignant lymphoma which accounted for one of the fifteen GPL studied. Although there is a low incidence of malignant lymphoma among GPL patients, pseudolymphoma should be considered as a precursor lesion with malignant potential.

show abstract

Gastric Pseudolymphomas Resembling Angioproliferative Lymph Node Hyperplasia

Cited by 9 publications

References 2 publications

Castleman's Disease of the Rectum: Report of a Case

Castleman's Disease of the Rectum: Report of a Case

Gastric pseudolymphoma: Its three subtypes and relation to lymphoma

Pseudolymphoma of the stomach. A clinicopathologic study of 15 cases

Contact Info

Product

Resources

About