Gastritis – facts and doubts

Abstract

IntroductionMany clinicians consider chronic gastritis to be equivalent to Helicobacter pylori infection. However, it is known that there are numerous other causes of the condition.AimDetermination of the incidence of gastritis in patients with dyspepsia referred for diagnostic endoscopy of the upper part of the digestive tract, identification of the parts of the stomach most frequently affected by the inflammation, as well as the impact of an insufficient number of collected samples on the correct diagnosis.Material and methodsUpper gastrointestinal endoscopy due to dyspepsia was performed in 110 patients. In the course of gastroscopy two biopsy specimens were collected for histopathological examination and towards H. pylori infection from the lesser and greater curvature in the antrum 3 cm from the pyloric sphincter, in the body – 4 cm proximally to the stomach angular incisure on the lesser curvature, and in the middle of the greater curvature, as well as in the subcardiac region on the side of the lesser and greater curvature.ResultsIn patients with dyspepsia H. pylori-negative chronic gastritis is more common than gastritis with accompanying H. pylori infection. Collection of too small a number of biopsy specimens results in failure to detect inflammatory changes and/or H. pylori infection, which may be limited to one part of the stomach. Biopsy specimens of gastric mucosa should be collected in compliance with the assumptions of the Sydney System. Helicobacter pylori infection in people with dyspepsia is now being reported more rarely than in the past (36%).ConclusionsIn patients with dyspepsia chronic H. pylori-negative gastritis is more common than gastritis with an accompanying H. pylori infection. Helicobacter pylori infection is not always equivalent to the presence of chronic gastritis.

Clinicopathological Correlation of Upper Gastrointestinal Tract Endoscopic Biopsies in a Tertiary Care Hospital in Rural Area of North India

“…These findings were in contrast to the study done by Wei et al where mean age group was 56 years 7 . Gastritis was found to be common in 31-40 years age group in the present study similarly, it was found to be common in 31-40 years in other studies & the incidence was also found to increase with age 8,9 . In the present study, gastric polyps were found more in females over 31-40 years, & 61-70 years age groups.…”

Clinicopathological Correlation of Endoscopic Esophageal Biopsies in a Tertiary Care Hospital in Rural Area of North India

“…The majority of the lesions were squamous cell carcinoma (76.9%) followed by chronic esophagitis. Though adenocarcinomas are on the rise, our study did not prove that might be due to limited patients undergoing esophageal endoscopic biopsies in contrast to stomach 8 . The most common site for squamous cell carcinoma was found to be lower one-third in the present study.…”

Histopathological Spectrum of Upper Gastrointestinal Tract Endoscopic Biopsies in a Tertiary Care Hospital in Rural Population in North India

“…These findings were in contrast to the study done by Wei et al where mean age group was 56 years8 . Gastritis was found to be common in 31-40 years age group in the present study similarly, it was found to be common in 31-40 years in other studies & the incidence was also found to increase with age9,10 . In the present study, gastric polyps were found more in females over 31-40 years, & 61-70 years age groups.…”