Gastrointestinal complications and extraintestinal manifestations of inflammatory bowel disease in Taiwan: A population-based study

Hsu, Yung-Cheng; Wu, Jia‐Feng; Lo, Yu-Cheng; Wang, Li‐Shu

doi:10.1016/j.jcma.2016.08.009

Cited by 28 publications

(23 citation statements)

References 34 publications

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“…A recent analysis of IBD clinical presentation using data extracted from NHIRD found that 11.2% of UC cases in Taiwan from 1998 to 2011 exhibited gastrointestinal complications and extraintestinal manifestations 24. During the 14-year study period, the prevalence of extraintestinal manifestations increased from 2.8% to 26.6%.…”

Section: Resultsmentioning

confidence: 99%

Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease

et al. 2017

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Ulcerative colitis (UC) is an inflammatory bowel disease characterized by chronic mucosal inflammation of the colon, and the prevalence and incidence of UC have been steadily increasing in Taiwan. A steering committee was established by the Taiwan Society of Inflammatory Bowel Disease to formulate statements on the diagnosis and management of UC taking into account currently available evidence and the expert opinion of the committee. Accurate diagnosis of UC requires thorough clinical, endoscopic, and histological assessment and careful exclusion of differential diagnoses, particularly infectious colitis. The goals of UC therapy are to induce and maintain remission, reduce the risk of complications, and improve quality of life. As outlined in the recommended treatment algorithm, choice of treatment is dictated by severity, extent, and course of disease. Patients should be evaluated for hepatitis B virus and tuberculosis infection prior to immunosuppressive treatment, especially with steroids and biologic agents, and should be regularly monitored for reactivation of latent infection. These consensus statements are also based on current local evidence with consideration of factors, and could be serve as concise and practical guidelines for supporting clinicians in the management of UC in Taiwan.

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Section: Resultsmentioning

confidence: 99%

Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease

et al. 2017

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“…In the ACCESS cohort, 19% of Asian IBD patients presented with EIMs . In Taiwan, EIMs were present among 11.9% of IBD patients; furthermore, the prevalence of EIMs increased from 2.3% in CD patients and 2.8% in UC patients to 25.9% and 26.6%, respectively, during a 14‐year follow‐up period …”

Section: Clinical Features Of Ibdmentioning

confidence: 99%

“…In western populations, joint manifestations (both peripheral and axial arthropathy) were the most common EIMs and affected 17–30% of IBD patients . Similarly, peripheral arthritis was the most common EIM in Taiwan and was present in 6.1% of IBD patients . Skin (5–15% vs. 0.3–1.8%) and ocular manifestations (3–6% to 0.1–0.3%) were more frequently reported in the West than in the East .…”

Section: Clinical Features Of Ibdmentioning

confidence: 99%

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The epidemiology of inflammatory bowel disease: East meets west

Mak

Zhao

et al. 2019

J of Gastro and Hepatol

446

291

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The incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade to become a global disease. The increasing number of studies on the incidence and course of IBD in East has enabled us to explore East versus West differences in the epidemiology of IBD which could enhance our understanding of the heterogeneity of the disease and eventually assist in the discovery of novel therapeutic targets and design of preventive strategies. Comparison of population‐based data in East and West reveals that the incidence of IBD has risen rapidly in East while plateauing in West. Furthermore, the clinical presentation and course of IBD differs between East and West with more patients in East presenting with complicated disease. Considering the scarcity of population‐based data from East and the lack of studies with long durations of follow‐up, it remains to be clarified whether these differences reflect true differences in disease presentation. The effects of genetic and environmental risk factors contributing to IBD also differ between Eastern and Western populations. Considering the differential effects of genetic and environmental risk factors in East and West, future studies should seek to discover novel genetic and environmental risk factors which might specifically apply to eastern populations. In this narrative review, we compare the epidemiology of IBD between eastern and western countries by summarizing evidence from population‐based cohort studies in the last ten years. Furthermore, we look at differences in genetic susceptibility and environmental triggers of IBD between East and West.

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“…Dysregulation of the immune interaction between enteric antigens and the enteral mucosa results in chronic, immune-mediated inflammation [3].…”

Section: Discussionmentioning

confidence: 99%

Clinical Cases of Crohn‘s Disease in Pediatric Hirschprung‘s Patients

Černiauskaitė¹,

Statkuvienė²,

Labanauskas³

et al. 2017

Austin J Gastroenterol

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Crohn's and Hirschsprung's diseases are two different conditions of intestinal tract though both of them are genetically predisposed. Each disease have genetic mutations in some genes, however there are no evidence that there are mutations common to both conditions. We present 3 clinical cases of patients who underwent surgery in infancy for Hirschsprung's disease. Later in early childhood all the patients developed clinical symptoms of inflammatory bowel disease and Crohn's disease was diagnosed. Both conditions were confirmed histologically. After introducing the treatment for Crohn's disease positive effect was shown. These cases raise the hypothesis that the two conditions may have similarities in etiology and pathogenesis and may represent a spectrum of intestinal inflammatory diseases in children.

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Gastrointestinal complications and extraintestinal manifestations of inflammatory bowel disease in Taiwan: A population-based study

Cited by 28 publications

References 34 publications

Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease

Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease

The epidemiology of inflammatory bowel disease: East meets west

Clinical Cases of Crohn‘s Disease in Pediatric Hirschprung‘s Patients

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