Gastrointestinal Manifestations of Collagen Diseases

Hostein, J; Fournet, J

doi:10.1159/000171154

Cited by 14 publications

(7 citation statements)

References 29 publications

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“…The commonest initial manifestation of the disease is Raynaud's phenomenon. In the advanced stage of the disease, lung, kidney and heart involvement may lead to death [1, 2, 6]. Gastrointestinal system involvement is frequently observed.…”

Section: Discussionmentioning

confidence: 99%

“…It may involve several vital organs (for example, the lung, heart, kidney, esophagus and intestine) and lead to progressive irreversible fibrosis in connective tissue [1, 2, 3, 4]. Its etiology and pathogenesis are still largely unknown.…”

Section: Introductionmentioning

confidence: 99%

“…It has two subgroups: diffuse systemic sclerosis, and limited disease with gastrointestinal manifestations possible in the subgroup. Clinically significant gastrointestinal involvement appears in around 50% of patients diagnosed with scleroderma in long-term follow-up [2]. This assumes the form of esophageal dysmotility, lower esophageal sphincter insufficiency, reflux, stricture, a reduction in motility in the intestine, wide-mouthed diverticles in the large intestine and rectal atonia in advanced cases [5].…”

Section: Introductionmentioning

confidence: 99%

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Esophagectomy in Scleroderma: Report of a Case

Yekeler

Gürsan²

2008

Case Rep Gastroenterol

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Scleroderma is a generalized autoimmune disease with variable involvement of the skin and major organs (esophagus, lung, heart and kidney). Scleroderma is essentially a skin disease that frequently involves the digestive system. In scleroderma, the esophagus is the most frequently affected organ of the digestive system, and esophageal dysmotility, reflux and stricture may be observed in the advanced stage. Balloon dilatation and bougienage are generally sufficient in patients developing stricture, and the number of cases in whom resection is performed is very low. In a 20-year-old patient with difficulty in taking even liquid foods, tests revealed sclerodermal involvement of the distal end of the esophagus and stricture. Esophageal resection and gastric replacement were performed. Such systemic diseases as scleroderma, although rare, must be considered in the differential diagnosis of nonmalignant dysphagia, and resection must be borne in mind as a surgical option in cases of advanced stricture.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Esophagectomy in Scleroderma: Report of a Case

Yekeler

Gürsan²

2008

Case Rep Gastroenterol

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“…Patients may have dysphagia accompanied by tracheal overflow and nasal regurgitation. Manometric abnormalities are observed in approximately 20% of patients, regardless of age, duration of illness, and presence of Raynaud's phenomenon [27]. An internal malignancy should be sought in those aged over 40 years because the disease arises secondary to malignancy in a subset of patients.…”

Section: Dermatomyositismentioning

confidence: 99%

Esophageal manifestations of dermatologic disease

Wise

Murray

2002

Curr Gastroenterol Rep

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This review describes those skin conditions, or conditions where skin involvement is a prominent feature, that may present with esophageal manifestations. These conditions have been categorized in many different ways. For the purposes of this review, esophageal manifestations of skin conditions are classified as bullous diseases, hyperkeratotic diseases, collagen vascular diseases, syndromes associated with cancer, and miscellaneous diseases.

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“…Gastrointestinal symptoms are relatively common and can be the initial manifestation of SLE. Oral lesions, mesenteric vasculitis, gastritis, pancreatitis, inflammatory bowel disease, protein-losing enteropathy, intestinal pseudo-obstruction, and esophageal dysmotility have been described [1][2][3]. Gastroparesis, literally "paralyzed stomach", is characterized by delayed gastric emptying in the absence of mechanical obstruction [4,5].…”

Section: Introductionmentioning

confidence: 99%

Gastroparesis in Systemic Lupus Erythematosus: A Case Report

Chou

2013

J Med Cases

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Gastrointestinal symptoms in systemic lupus erythematosus (SLE) are varied and can involve any part of the gastrointestinal tract. Although esophageal dysmotility and intestinal pseudo-obstruction have been described, the occurrence of gastroparesis in SLE patients has yet to be the subject of a medical report. We present a case of a 29-year-old woman with SLE whose predominant symptom is persistent nausea and vomiting with no evidence of mechanical obstruction.

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Gastrointestinal Manifestations of Collagen Diseases

Cited by 14 publications

References 29 publications

Esophagectomy in Scleroderma: Report of a Case

Esophagectomy in Scleroderma: Report of a Case

Esophageal manifestations of dermatologic disease

Gastroparesis in Systemic Lupus Erythematosus: A Case Report

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