Gastrosquisis: ¿una pandemia con tasas en aumento? Experiencia del estudio colaborativo latino americano de malformaciones congénitas (ECLAMC) en Chile. Período 1982-2014

Herrera, Jesús; Essedin, Lucas Karachon; Ovalle, Lucía Cifuentes; Assar, Rodrigo

doi:10.1016/j.rchipe.2016.06.003

Cited by 13 publications

(12 citation statements)

References 21 publications

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“…The association between young maternal age and gastroschisis is a well–documented risk factor 14–16,19,20 . However, the increase in gastroschisis prevalence is not because of an increase in teen births, since birth rates have decreased among mothers <25 years, and the highest increase in prevalence trend occurred among mothers aged 30–34 years.…”

Section: Discussionmentioning

confidence: 99%

Increasing prevalence, time trend and seasonality of gastroschisis in São Paulo state, Brazil, 2005–2016

Calderon¹,

Santos

Abreu

et al. 2019

Sci Rep

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To estimate the gastroschisis seasonality and trend of prevalence in recent years, stratified by maternal age and geographical clusters of São Paulo state, a population–based study was designed. We used data from the Live Births Information System (SINASC) in São Paulo state, Brazil, from 2005 to 2016. Trends of prevalence were evaluated for the specific subgroups using the Prais–Winsten regression model, and the Durbin–Watson test was used, to estimate the regression coefficient, the annual percent change (APC), and 95% confidence interval (CI). We observed 1576 cases of gastroschisis among 7,317,657 live births (LB), a prevalence of 2.154 (95% CI: 2.047–2.260) per 10,000 LB which included, 50.6% males, 67.4% Caucasians, 53.4% preterm births, and 80.9% caesarean births. The prevalence of gastroschisis significantly increased by 2.6% (95% CI: 0.0–5.2) per year, and this trend was higher in mothers aged 30–34 years (APC: 10.2, 95% CI: 1.4–19.4) than in mothers of other age groups. Between 2011 and 2016, we identified the existence of seasonality based on the date of conception in the middle months of the year (p = 0.002). This is the first and largest population–based study summarizing current epidemiology and identifying trend of prevalence of gastroschisis in São Paulo state.

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Section: Discussionmentioning

confidence: 99%

Increasing prevalence, time trend and seasonality of gastroschisis in São Paulo state, Brazil, 2005–2016

Calderon¹,

Santos

Abreu

et al. 2019

Sci Rep

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“…The adjudged reason for such an increase in the prevalence could not be substantiated. A few authors suggested increasing prenatal ultrasound use, which makes the clinician be able to pick up the at-risk fetus very early [29,30]. Meanwhile, a few cases were seen in Southern America, covering Honduras, Chile, Brazil, and then Australia, etc.…”

Section: Epidemiologymentioning

confidence: 99%

“…Meanwhile, a few cases were seen in Southern America, covering Honduras, Chile, Brazil, and then Australia, etc. [29,30]. One literature reported that there had been an estimated 300% increase in the incidence of GS from 1994 up till 2015, otherwise regarded as a "Gastroschisis pandemic which is strongly related to low maternal age that is maternal age <20 years" [29,30].…”

Section: Epidemiologymentioning

confidence: 99%

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Giant gastroschisis with complete gastric herniation: A case report and review of the literature

Alegbeleye¹

2020

Iberoam J Med

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Introduction: We report a case of gastroschisis seen in our center, highlighting the rarity of this clinical entity. The author equally reviewed the existing literature covering the epidemiology, etiopathogenesis, management options, and outcomes of gastroschisis in low-income countries in sub-Saharan Africa and compares the reports with middle-income and high-income countries across the world. Case presentation: A preterm female neonate with a clinical diagnosis of gastroschisis at a primary care center was referred to the Neonatology Service of our tertiary care institution. She received optimal resuscitation and interdisciplinary management. Besides, the baby underwent an initial covering with an improvised silo bag of exposed bowel with unfavorable outcomes. Conclusion: The specific etiological factors for gastroschisis are yet to be established. The condition is considered a multifactorial disease. More frequently than ever, it's becoming easy to make prenatal diagnosis utilizing ultrasonography with high yield. Gastroschisis is a low-prevalence disease with an excellent prognosis if initial management is adequate. Interestingly, the condition requires highly skilled personnel of both specialized and primary care. Once the clinicians are well equipped, they can readily ensure correct initial management. Besides, the patient can equally benefit from an appropriate and timely referral to tertiary care centers to avoid future complications.

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“…Several communications have reported a significant increase in the prevalence of gastroschisis at birth in the last three decades. It is referred to as "a pandemic strongly associated to low maternal age" in many countries [4]. In gastroschisis, unlike omphalocele, there is no membranous covering over the intestine, which is markedly edematous and erythematous and is often enclosed in a fibrin mat.…”

Section: м а макароваmentioning

confidence: 99%

Peculiarities of surgical treatment of gastrointestinal tract combined congenital malformations in newborns

Makarova

2017

ZMJ

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Congenital gastrointestinal (GI) malformations make up 21-25 % of all congenital anomalies and require surgical correction in the neonatal period.The aim was to analyze the methods of operative treatment of hard composite congenital gastrointestinal malformations in infants.Materials and Methods. There were 13 newborns with gastroschisis, omphalocele and esophageal atresia combined with intestinal atresia, anal atresia and also with congenital heart defects in our study. Results.We have designed new preoperative care strategies for the newborns. All combined GI defects were corrected in one step. In gastroschisis and omphalocele in combination with small intestine atresia we made a plastic of anterior abdominal wall, bowel segment resection and anastomosis end-to-end. In esophageal atresia and atresia of the anus direct esophagoesophagoanastomosis was applied with suturing of tracheoesophageal fistula, also in two patients proctoplasty by Pena 2 was carried out, and in one patient with high anal atresia colostomy was applied, which was closed in the age of 6 months. In case of esophageal atresia combined with small intestine atresia direct esophago-esophagoanastomosis with tracheoesophageal fistula suturing was carried out, and resection of the bowel segment with anastomosis end-to-end was applied. In a patient with a combination of esophageal atresia and duodenal obstruction esophagoplasty and closure of tracheoesophageal fistula with anastomosis by Kimur was made. Preference was given to the combined anesthesia with neuraxial blockade. Postoperative care included prolonged artificial lung ventilation, anesthesia, parenteral nutrition, antibacterial and antifungal medicines.Conclusions. One-step correction of the congenital GI malformations in newborns is effective and it gives opportunity to achieve the best results with a single surgical intervention. Extremely important links of the combined GI defects therapy is timely and balanced preoperative preparation, anesthetic management with the advantage of neuraxial blockade usage, as well as careful postoperative management of the patient.Особливості хірургічного лікування комбінованих вроджених вад розвитку шлунково-кишкового тракту в новонароджених М. О. МакароваВроджені вади розвитку шлунково-кишкового тракту (ШКТ) становлять 21-25 % усіх уроджених аномалій і потребують хірургічної корекції у періоді новонародженості.Мета роботи -аналіз методів оперативного лікування тяжких комбінованих уроджених вад розвитку ШКТ у новонароджених.Матеріали та методи. Під спостереженням перебували 13 новонароджених дітей із гастрошизисом, омфалоцеле та атрезією стравоходу в комбінації з атрезією тонкого кишечника або ануса, а також із вродженими вадами серця.Результати. Розробили схеми передопераційної підготовки для новонароджених. Усі комбіновані вади ЖКТ скоректовані за один етап. При гастрошизисі та омфалоцеле в поєднанні з атрезією тонкої кишки проводилась пластика передньої черевної стінки, резекція ділянки кишки та накладення анастомозу кінець у кінець. При атрезії стра...

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Gastrosquisis: ¿una pandemia con tasas en aumento? Experiencia del estudio colaborativo latino americano de malformaciones congénitas (ECLAMC) en Chile. Período 1982-2014

Abstract: There has been a significant increase in the gastroschisis prevalence at birth in Chile from 1995, and this anomaly is associated with a low maternal age.

Cited by 13 publications

References 21 publications

Increasing prevalence, time trend and seasonality of gastroschisis in São Paulo state, Brazil, 2005–2016

Increasing prevalence, time trend and seasonality of gastroschisis in São Paulo state, Brazil, 2005–2016

Giant gastroschisis with complete gastric herniation: A case report and review of the literature

Peculiarities of surgical treatment of gastrointestinal tract combined congenital malformations in newborns

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