We study symmetries of quantum field theories involving topologically distinct sectors of the field space. To exhibit these symmetries we define special gauge invariant observables, which we call the qq-characters. In the context of the BPS/CFT correspondence, using these observables, we derive an infinite set of Dyson-Schwinger-type relations. These relations imply that the supersymmetric partition functions in the presence of Ω-deformation and defects obey the Ward identities of two dimensional conformal field theory and its q-deformations. The details will be discussed in the companion papers.