Platform Screen Doors (PSDs) have been widely used in modern Asian and European metro systems due to the advantages of safety, comfort for passengers. Unfortunately, someone or something will be caught by PSDs and metro doors occasionally, which may lead to serious accidents. Therefore, the foreign object detection between PSDs and metro doors is a burning problem. Moreover, this problem is a challenging and still largely under-explored topic. In recent years, we have seen significant improvements in generic object detection built on deep learning techniques. Accordingly, this paper adopts deep learning technologies to address the problem of foreign object detection between PSDs and metro doors. To the best of our knowledge, this is the first attempt to use deep learning to solve the problem. To realize this, a dataset including 984 real-world images (with 600 × 480 pixels) labeled for six types of foreign objects (bag, bottle, person, plastic bag, umbrella, other) is developed. Then, we compared the performance of some state-of-the-art object detection algorithms (such as You Only Look Once-YOLOv3, Single Shot MultiBox Detector-SSD, and CenterNet) on the dataset. Experimental results demonstrate that the foreign object detection algorithms based on deep neural networks have achieved excellent results, which not only improves the accuracy of detection but also give the categories of foreign objects. YOLOv3-tiny can achieve the fastest detection speed, up to 200 Frame Per Second (FPS); CenterNet can achieve the best detection results, up to 99.7% mean Average Precision (mAP).