Ge, A Very Common Red‐Cell Antigen

Rosenfield, R. E.; Haber, Gladys V.; Kissmeyer‐Nielsen, F.; Jack, James A.; Sanger, Ruth; Race, R. R.

doi:10.1111/j.1365-2141.1960.tb06251.x

Cited by 63 publications

(25 citation statements)

References 3 publications

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“…To our knowledge, Mrs. M. C. is the thirteenth case of anti-Gerbich reported in the world literature [2]. The antibody is capable of producing erythroblastosis fetalis, as evidenced by positive direct Coombs tests on the cells of three previously reported healthy infants [3] and the case presently under discussion. In no instance, however, has an infant required exchange transfusion.…”

Section: Discussionmentioning

confidence: 90%

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Auto-Donation in the Management of Placenta Previa and Erythroblastosis in a Pregnancy Complicated by Gerbich Iso-Immunization

Peddle¹,

Josephson²,

Lawton³

1970

Vox Sanguinis

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Section: Discussionmentioning

confidence: 90%

“…Gerbich is a high-frequency antigen defined by an antibody first reported in 1960 [3]. To our knowledge, Mrs. M. C. is the thirteenth case of anti-Gerbich reported in the world literature [2].…”

Section: Discussionmentioning

confidence: 98%

Auto-Donation in the Management of Placenta Previa and Erythroblastosis in a Pregnancy Complicated by Gerbich Iso-Immunization

Peddle¹,

Josephson²,

Lawton³

1970

Vox Sanguinis

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“…The frequency of Ge (a-) persons in certain Melanesian peoples exceeds that of Rhesus negative persons in most European communities, and moreover anti-Gea is a common 'naturallyoccurring' antibody. Haemolytic transfusion reactions due to 'naturallyoccurring' anti-Gea have not been identified in New Guinea, but certainly the antibody can be stimulated by both pregnancy [8] and transfusion [6], and the first example identified in New Guinea is extremely potent in vitro.…”

Section: Discussionmentioning

confidence: 99%

“…The Gerbich red cell antigen (Gea), one of the most widely-distributed of blood group antigens [8], has been briefly reported [1] as absent in a propor tion of Melanesians from certain ethnic groups in Papua and New Guinea. The investigations followed on from the finding that a strong immune IgG type antibody formed by a New Guinean woman (Impuru) as the result of blood transfusion was anti-Gerbich (anti-Gea), and that she was Ge (a-), as were her husband and surviving child.…”

mentioning

confidence: 99%

The Gerbich Blood Group System, Especially in Melanesians

Booth

McLoughlin²

1972

Vox Sanguinis

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Investigations of the Gerbich blood group system in Melanesians of Papua/ New Guinea are described. Over 50% of members of certain population groups are Gerbich negative, and anti-Gea (‘naturally-occurring’) is present in about 10% of Ge (a-) people. The distribution of populations with high Ge (a-) incidence is not explicable at present. A Gerbich antibody (anti-Ge 1) with a new specificity has been investigated, and the following phenotypes are now distinguishable: Ge 1, 2, 3 (some Melanesians and almost all others), Ge -1, 2, 3 (some Melanesians), Ge -1, -2, 3 (‘Yus’ type, not found in Melanesians), Ge -1, -2, -3 (Gerbich negatives).

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“…Since Rosenfield et al [1] reported in 1960 three antibodies that defined the very common red blood cell antigen Gerbich, rare Gerbich(Ge)-negative red cells have been identified in people of European, Mexican, South American, Indian, Negro and Oriental origin [2]. Two types of Genegative red cell membranes, Gerbich and Leach, are known [2], In the Gerbich type, the sialoglycoproteins P (P-SGP) and y (y-SGP), important for maintaining cell shape, are absent.…”

mentioning

confidence: 99%