Geant4 used in medical physics and hadrontherapy technique

Tang, Shi-Biao; Yin, Zejie; Huang, Huan; Cheng, Yan; Cheng, Fu-Hui; Mao, Feng-Hua

doi:10.1016/s1001-8042(06)60051-1

Cited by 9 publications

(3 citation statements)

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“…In order to test the accuracy of the calculations in order to find the appropriate doses of protons and carbon beams in the water phantom, the Bragg curves of 80,100, 120 and 140 MeV energy proton beams and 1.6, 2.4 and 3.0 GeV energy carbon beams normalized to the maximum dose in the water phantom were compared with the literature [13][14][15][16][17][18][19][20][21][22][23]. By comparison, an average difference of 3.37% for the two particles was observed is generally not significant and is within acceptable limits (<5%) in medical physics.…”

Section: Resultsmentioning

confidence: 99%

Analysis of Bragg curve parameters and lateral straggle for proton and carbon beams

Ekinci

Bostancı

Dagli³

et al. 2021

Commun.Fac.Sci.Univ.Ank.Series A2-A3: Phys.Sci. and Eng.

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Heavy ions have varying effects on the target. The most important factor in comparing this effect is Linear Energy Transfer (LET). Protons and carbons are heavy ions with high LET. Since these ions lose energy through collisions as they move through the tissue, their range is not long. This loss of energy increases along the way, and the maximum energy loss is reached at the end of the range. This whole process is represented by the Bragg curve. The input dose of the Bragg curve, full width at half maximum (FWHM) value, Bragg peak amplitude and position, and Penumbra thickness are important factors in determining which particle is advantageous in tumor treatment. While heavy ions move through the tissue, small deviations occur in their direction of travel due to Coulomb collisions. These small deviations cause lateral straggle in the dose profile. Lateral straggle is important in determining the type and energy of the particle used in tumor treatments close to critical organs. In our study, when the water phantom of protons and carbon beams with different energies is taken into consideration, the input dose, FWHM value, peak amplitude and position, penumbra thickness and lateral straggle are calculated using the TRIM code and the results are compared with Monte Carlo (MC) simulation. It was found that the proton has an average of 63% more FWHM and 53% more Penumbra than the carbon ion. The carbon ion has an average of 28-45 times greater Bragg peak amplitude at the same Bragg peak location than the proton. It was observed that the proton scattered approximately 70% more in lateral straggle. The difference was found to be around 1.32 mm. In line with all these results, the most commonly used proton and carbon heavy ions in hadron therapy applications were compared.

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Section: Resultsmentioning

confidence: 99%

Analysis of Bragg curve parameters and lateral straggle for proton and carbon beams

Ekinci

Bostancı

Dagli³

et al. 2021

Commun.Fac.Sci.Univ.Ank.Series A2-A3: Phys.Sci. and Eng.

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“…GEANT4 19 is a promising Monte Carlo (MC) simulation code and has been widely applied in dose calculation for medical physics and radiation protection. [20][21][22][23][24][25][26][27] In this study, GEANT4 (version 4.10.1.p02) was adopted to simulate the proton transportation under magnetic fields. Three types of geometry configurations were constructed and investigated using GEANT4.…”

Section: Methodsmentioning

confidence: 99%

Modulation of lateral positions of Bragg peaks via magnetic fields inside cancer patients: Toward magnetic field modulated proton therapy

et al. 2017

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The BP positions can be intentionally modulated to produce uniform tumor doses under the magnetic fields inside cancer patients. In some special cases, the vital organs surrounding the tumor can almost be exempted from proton irradiations without sacrificing tumor dose coverage through MMPT. For the tumors inside parallel organs, the parallel organ volume receiving proton irradiations was largely reduced through MMPT. The results of this study can serve as beneficial implications for future proton therapy studies with reduced vital organ damage and complications.

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“…The presented investigation was based on the Monte Carlo computer simulations with the use of the GEANT4 software in the version 4.9.3. The GEANT4 code is recommended by many scientists for application in proton and other kinds of radiotherapy 11,6,[12][13][14] because it provides all physical processes occurring during the emission of proton therapeutic beams, based on extensive data bases of experimental parameters, cross-section, etc. The majority of physical process models is based on experimental data bases which makes it possible to obtain very accurate results.…”

Section: Methodsmentioning

confidence: 99%

The determination of a dose deposited in reference medium due to (p,n) reaction occurring during proton therapy

Dawidowska

Paluch-Ferszt

Konefał

2014

Reports of Practical Oncology & Radiotherapy

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Geant4 used in medical physics and hadrontherapy technique

Cited by 9 publications

References 0 publications

Analysis of Bragg curve parameters and lateral straggle for proton and carbon beams

Analysis of Bragg curve parameters and lateral straggle for proton and carbon beams

Modulation of lateral positions of Bragg peaks via magnetic fields inside cancer patients: Toward magnetic field modulated proton therapy

The determination of a dose deposited in reference medium due to (p,n) reaction occurring during proton therapy

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