Gender differences exist in the hip joint moments of healthy older walkers

Boyer, Katherine A.; Beaupré, Gary S.; Andriacchi, Thomas P.

doi:10.1016/j.jbiomech.2008.09.030

Cited by 65 publications

(54 citation statements)

References 46 publications

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“…Further studies should elucidate this aspect for a better understanding of sex-related dimorphism in knee pathology and improvement of related surgical treatments. In other fields, a gender specific research is already on its way [7,30].…”

Section: Discussionmentioning

confidence: 99%

Outcome Of Autologous Matrix Induced Chondrogenesis (Amic) In Cartilage Knee Surgery: Data Of The Amic Registry

Gille¹,

Anders²,

Volpi³

et al. 2013

Arthroscopy: The Journal of Arthroscopic & Related Surgery

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Introduction Autologous Matrix-Induced Chondrogenesis (AMIC) is an innovative treatment for localized fullthickness cartilage defects combining the well-known microfracturing with collagen I/III scaffold. The purpose of this analysis was to evaluate the medium-term results of this enhanced microfracture technique for the treatment of chondral lesions of the knee. Methods and materials Patients treated with AMIC (Chondro-Gide Ò , Geistlich Pharma, Switzerland) were followed using the AMIC Registry, an internet-based tool to longitudinally track changes in function and symptoms by the Lysholm score and VAS. Results A series of 57 patients was enrolled. The average age of patients (19 females, 38 males) was 37.3 years (range 17-61 years). The mean defect size of the chondral lesions was 3.4 cm 2 (range 1.0-12.0 cm 2 ). All defects were classified as grade III (n = 20) or IV (n = 37) according to the Outerbridge classification. Defects were localized at the medial (n = 32) or lateral (n = 6) condyle, at the trochlea (n = 4) and at the patella (n = 15). The follow-up period was 2 years. The majority of patients were satisfied with the postoperative outcome, reporting a significant decrease of pain (mean VAS preop = 7.0; 1 year postop = 2.7; 2 years postop = 2.0). Significant improvement of the mean Lysholm score was observed as early as 1 year after AMIC and further increased values were noted up to 2 years postoperatively (preop. 50.1, 1 year postop. 79.9, 2 year postop. 85.2). Conclusions AMIC is an effective and safe method of treating symptomatic chondral defects of the knee. However, further studies with long-term follow-up are needed to determine if the grafted area will maintain structural and functional integrity over time. Level of evidence Prognostic study, Level IV.

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Section: Discussionmentioning

confidence: 99%

Outcome Of Autologous Matrix Induced Chondrogenesis (Amic) In Cartilage Knee Surgery: Data Of The Amic Registry

Gille¹,

Anders²,

Volpi³

et al. 2013

Arthroscopy: The Journal of Arthroscopic & Related Surgery

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“…In addition, the participants in this study were males in excellent physical condition. Because of certain sex-related differences in walking [46] and running [47] mechanics, caution should be exercised in generalizing these results to females and persons with limited neuromuscular capacities. In this study, joint kinetics determined by inverse dynamics approach reflects the net product of the all muscles crossing the joint.…”

Section: Future Studies and Limitationsmentioning

confidence: 99%

Which muscles compromise human locomotor performance with age?

Kulmala

Korhonen

Kuitunen

et al. 2014

J. R. Soc. Interface.

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Ageing leads to a progressive decline in human locomotor performance. However, it is not known whether this decline results from reduced joint moment and power generation of all lower limb muscle groups or just some of them. To further our understanding of age-related locomotor decline, we compare the amounts of joint moments and powers generated by lower limb muscles during walking (self-selected), running (4 m s 21) and sprinting (maximal speed) among young, middle-aged and old adults. We find that age-related deficit in ankle plantarflexor moment and power generation becomes more severe as locomotion change from walking to running to sprinting. As a result, old adults generate more power at the knee and hip extensors than their younger counterparts when walking and running at the same speed. During maximal sprinting, young adults with faster top speeds demonstrate greater moments and powers from the ankle and hip joints, but interestingly, not from the knee joint when compared with the middle-aged and old adults. These findings indicate that propulsive deficit of ankle contributes most to the age-related locomotor decline. In addition, reduced muscular output from the hip rather than from knee limits the sprinting performance in older age.

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“…More than 46 million people reported having arthritis (60.8% women), and almost 19 million people reported arthritis affected their ability to do everyday activities (63% women) [33]. Women have different gait patterns in response to osteoarthritis [12], report worse symptoms of knee osteoarthritis than men with similar radiographic severity [10], have increased rates of cartilage loss than men [19], and have greater hip degeneration [7]. Women also seek care from physicians for hip and knee problems more often than men, and this trend has persisted over the last 10 years [3].…”

Section: Why Are Sex and Gender Important In Research?mentioning

confidence: 99%

Examining Sex and Gender Disparities in Total Joint Arthroplasty

Novicoff

Saleh

2011

Clinical Orthopaedics &Amp; Related Research

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Background Total joint arthroplasty (TJA) is remarkably successful for treating osteoarthritis: most patients see substantial gains in function. However, there are considerable geographic, racial, and gender variations in the utilization of these procedures. The reasons for these differences are complex. Questions/purposes We examined sex and gender disparities in TJA. Methods Through Medline/PubMed searches, we identified 632 articles and from these selected 61 for our review. Where are we now? A number of factors might explain sex and gender disparities in TJA: underrepresentation in clinical trials, differences in willingness to undergo surgery, pain responses to underlying disease and treatment, patient-physician relationships, treatment preferences, provider-level factors such as physician-patient communication style, and system-level factors such as access to specialist care. Since women have a higher prevalence of arthritis and degenerative joint diseases and overall demand for these procedures will continue to grow, the need to understand why there is a gap in utilization based on gender is imperative. Where do we need to go? Understanding what exactly is meant by ''disparity'' is essential because it is possible anatomic factors may have different impacts on utilization from cultural factors. Ideally, information about these factors should be integrated into the decision-making process so that patients and providers can make the most informed choice about whether or not to undergo the procedure. How do we get there? To better understand all of the potential reasons for how anatomic and cultural factors related to sex and gender might impact decision-making and overall utilization of TJA, more research focusing on these factors must be designed and carried out.

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Gender differences exist in the hip joint moments of healthy older walkers

Cited by 65 publications

References 46 publications

Outcome Of Autologous Matrix Induced Chondrogenesis (Amic) In Cartilage Knee Surgery: Data Of The Amic Registry

Outcome Of Autologous Matrix Induced Chondrogenesis (Amic) In Cartilage Knee Surgery: Data Of The Amic Registry

Which muscles compromise human locomotor performance with age?

Examining Sex and Gender Disparities in Total Joint Arthroplasty

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