Gender differences in central obesity: Implications for cardiometabolic health in South Asians

Prasad, D.S.; Kabir, Zubair; Devi, Katyayini; Peter, P.; Das, B. C.

doi:10.1016/j.ihj.2020.04.008

Cited by 17 publications

(11 citation statements)

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“…The prevalence of overweight and obesity was 28.6% and 12.8%, respectively as reported by Thakur et al (2016) in Punjab. Central obesity was higher among women (Prasad et al 2020 ;Deepa et al 2009) and the present study's gender differences are in concordance with the previous studies. Lipids (except HDL-C) and lipoprotein indices were higher in obese patients as well as LDL-C and LDL-C/HDL-C in overweight patients while HDL-C levels higher in patients with normal weight which is in agreement with the study carried out by Manawat et al (2020).…”

Section: Discussionsupporting

confidence: 93%

Recent trends in anthropometric indices and lipoprotein indices as non-invasive biomarkers of atherosclerosis and coronary heart diseases in general population of Amritsar city

Monu

Gandhi

2022

Preprint

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Elevated low density lipoprotein cholesterol levels in circulation may get deposited in coronary arteries and result in atherosclerotic plaques at an early age and act as risk factor for cardiovascular diseases. More recent and detailed anthropometric indices in addition to traditional indices were assessed in this study along with lipid profile and lipoprotein indices in urban population (n=100) of Amritsar, Punjab. n=48 subjects comprised the case group and n=52 subjects the control group. Study was approved by the Institutional Ethics Committee of Guru Nanak Dev University and individual voluntary written informed consent was provided by the study group. 46% of cases were obese and lipids and lipoprotein indices were significantly higher in obese group while low density lipoprotein cholesterol and low density lipoprotein cholesterol/high density lipoprotein cholesterol also in overweight category. Factor analysis extracted the 7 components out of 23 variables with a cummulative variance of 81.45%. Females had higher central obesity, waist hip ratio, waist height ratio and body adiposity index. Pearson’s correlation analysis revealed a positive significant association of age (r=0.363, p=0.027), socio-economic status (r=0.328,p=0.023), waist hip ratio (r=0.298,p=0.042), waist height ratio (r=0.864,p=0 000) and body mass index (r=0.794,p=0.000) with low density lipoprotein cholesterol levels and of gender with atherogenic index(r=0.363,p=0.011). Also, a significant correlation of total body fat mass with atherogenic index(r=0.286,p=0.048) and and body roundness index with low density lipoprotein(r=0.345,p=0.016) was observed. Multivariate regression analysis revealed age (B=0.318,t=2.380,p=0.022) and gender (B=0.370,t=2.687,p=0.010) to be significant predictors of body roundness index as well as age (B=0.139,t=2.307,p=0.027) of low density lipoprotein cholesterol. The highest prediction accuracy was showed by waist circumference (AUC=0.597) and the least by a body shape index (AUC=0.458) as revealed by Receiver Operating Characteristics analysis.

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Section: Discussionsupporting

confidence: 93%

Recent trends in anthropometric indices and lipoprotein indices as non-invasive biomarkers of atherosclerosis and coronary heart diseases in general population of Amritsar city

Monu

Gandhi

2022

Preprint

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“…This higher figure of central obesity attributed to increased gender differences ( 36 , 51 ), educational attainment and socioeconomic status ( 52 ), physical inactivity ( 26 ), and other diseases such as diabetes and hypertension ( 25 , 53 ). Consistent with our result, the global prevalence of central obesity was reported to be 41.5% ( 54 ).…”

Section: Discussionmentioning

confidence: 99%

Prevalence of central obesity and associated factors in Ethiopia: A systematic review and meta-analysis

et al. 2022

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IntroductionObesity is a global public health concern that is now on the rise, especially in low- and middle-income nations. Despite the fact that there are several studies reporting the prevalence of central obesity among adults in Ethiopia, there is a lack of a systematic review and meta-analysis synthesizing the existing observational studies. Therefore, this systematic review and meta-analysis aimed to determine the prevalence of central obesity and its associated factors in Ethiopia.MethodsOnline libraries such as PubMed, Google Scholar, Scopus, Science Direct, and Addis Ababa University were searched. Data were extracted using Microsoft Excel and analyzed using STATA statistical software (v. 16). Forest plots, Begg’s rank test, and Egger’s regression test were all used to check for publication bias. To look for heterogeneity, I2 was computed, and an overall estimated analysis was carried out. Subgroup analysis was done by region and study setting. In addition, the pooled odds ratio for related covariates was calculated.ResultsOut of 685 studies assessed, 20 met our criteria and were included in the study. A total of 12,603 people were included in the study. The prevalence of central obesity was estimated to be 37.31% [95% confidence interval (CI): 29.55–45.07]. According to subgroup analysis by study region and setting, the highest prevalence was observed in the Dire Dawa region (61.27%) and community-based studies (41.83%), respectively. Being a woman (AOR = 6.93; 95% CI: 3.02–10.85), having better socioeconomic class (AOR = 5.45; 95% CI: 0.56–10.34), being of age 55 and above (AOR = 5.23; 95% CI: 2.37–8.09), being physically inactive (AOR = 1.80; 95% CI: 1.37–2.24), being overweight (AOR = 4.00; 95% CI: 2.58–5.41), being obese (AOR = 6.82; 95% CI: 2.21–11.43), and having hypertension (AOR = 3.84; 95% CI: 1.29–6.40) were the factors associated with central obesity.ConclusionThe prevalence of central obesity was high in Ethiopia. Being a woman, having a higher socioeconomic class, being older, being physically inactive, being overweight or obese, and having hypertension were all associated. Therefore, it is vital for the government and health organizations to design and implement preventive measures like early detection, close monitoring, and positive reversal of central obesity in all patients and the general population. High-quality investigations on the prevalence of central obesity in the Ethiopian people are required to better understand the status of central obesity in Ethiopia.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO, identifier: CRD42022329234.

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“…A contemporary study from the Asia-Pacific region examined 1178 participants for gender differences with respect to obesity and its associated cardiometabolic risk factors. [ 13 ] The Asia-Pacific guidelines were used to define obesity. Women were found to have a higher age-adjusted central obesity in about half of the subjects.…”

Section: E Pidemiologymentioning

confidence: 99%

Gender Disparities in People Living with Obesity - An Unchartered Territory

Kapoor

Arora

Kalra

2021

Journal of Mid-Life Health

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Gender is an important risk factor for the development of obesity. Female gender is associated with twice the risk of being overweight or having obesity. Women are also at higher risk for developing obesity-related physical and psychological comorbidities and have a twofold higher mortality risk than overweight men. Several risk factors have been described to explain the gender bias associated with an obese phenotype and these disparities have far-reaching implications on the medical, psychosocial, and the economical impact of an individual. Despite extensive awareness about gender differences related to obesity, this is still considered as an unchartered territory in obesity medicine. This is probably because of the complex multiple dimensions involved with the understanding of subject coupled with the lack of composite outcomes measures that could assist in the study of these factors. In this scoping review, we share the existing literature regarding the magnitude of gender disparities and gender discrimination in people living with obesity. We describe key factors leading to this gender bias and the impact of this discrimination on the psychological, social, and metabolic health of a given individual with obesity. We also discuss the possible implications of gender disparities on treatment of obesity which may help reduce the current mortality gap between overweight women and men.

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Gender differences in central obesity: Implications for cardiometabolic health in South Asians

Cited by 17 publications

References 11 publications

Recent trends in anthropometric indices and lipoprotein indices as non-invasive biomarkers of atherosclerosis and coronary heart diseases in general population of Amritsar city

Recent trends in anthropometric indices and lipoprotein indices as non-invasive biomarkers of atherosclerosis and coronary heart diseases in general population of Amritsar city

Prevalence of central obesity and associated factors in Ethiopia: A systematic review and meta-analysis

Gender Disparities in People Living with Obesity - An Unchartered Territory

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