Gender differences in prevalence and correlates of antisocial personality disorder among heroin dependent users in compulsory isolation treatment in China

Yang, Mei; Mamy, Jules; Zhou, Liang; Liao, Yanhui; Wang, Qiang; Seewoobudul, Vasish; Xiao, Shuiyuan; Hao, Wei

doi:10.1016/j.addbeh.2013.11.003

Cited by 9 publications

(11 citation statements)

References 32 publications

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“…Our study showed much higher prevalence rates of PDs among male MA users than general population (24, 25), schizophrenia patients (26), and female prison inmates (27). The rank of the PDs' prevalence in male MA-dependent users was consistent with a report for male heroin-dependent users in the same setting in China (28). The present study showed relatively higher rates of PDs when compared with Yang's study (28), such as antisocial PD (75.5 vs. 54.2%), borderline PD (23.7 vs. 22.7%), avoidant PD (17.3 vs. 13.9%), paranoid PD (15.7 vs. 8.5%), and negativistic PD (14.9 vs. 11.9%).…”

Section: Discussionsupporting

confidence: 88%

“…The rank of the PDs' prevalence in male MA-dependent users was consistent with a report for male heroin-dependent users in the same setting in China (28). The present study showed relatively higher rates of PDs when compared with Yang's study (28), such as antisocial PD (75.5 vs. 54.2%), borderline PD (23.7 vs. 22.7%), avoidant PD (17.3 vs. 13.9%), paranoid PD (15.7 vs. 8.5%), and negativistic PD (14.9 vs. 11.9%). These differences of PD rates could be mainly due to the different populations (MA vs. heroin).…”

Section: Discussionsupporting

confidence: 88%

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Prevalence Rates of Personality Disorder and Its Association With Methamphetamine Dependence in Compulsory Treatment Facilities in China

et al. 2018

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Methamphetamine use is popular and rapidly increasing in China, and the co-occurrence of personality disorders has an impact on treatment outcomes and may increase vulnerability of developing dependence. The aim of the present study was to investigate the prevalence rates of personality disorders in methamphetamine users and further explore the association between personality disorders and methamphetamine use status. Five hundred and seventy-seven male methamphetamine users were recruited. The self-developed questionnaire was used for demographics, and a Structural Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) (SCID-I/II) was performed covering psychiatric diagnosis. Our study found the prevalence of antisocial personality disorder in male methamphetamine users was 71.4%, followed by borderline (20.2%) and obsessive-compulsive (17.9%) personality disorder. Borderline and antisocial personality disorders were found to be risk factors of methamphetamine dependence (adjusted odds ratio = 2.891, p = 0.007 and adjusted odds ratio = 1.680, p = 0.042). These findings suggested personality disorders were highly prevalent in male methamphetamine users, and the comorbidity of antisocial and borderline personality disorders are especially associated with methamphetamine dependence.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionsupporting

confidence: 88%

Prevalence Rates of Personality Disorder and Its Association With Methamphetamine Dependence in Compulsory Treatment Facilities in China

et al. 2018

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“…Nicotine is a legal drug believed to serve as a gateway for subsequent illegal drug use via both biological and psychosocial mechanisms (Senjo, 2005, Green, 2006, Alegria et al, 2013). ASPD, a more common disorder in males than in females in general (Swanson et al, 1994, Moran, 1999, Grant et al, 2004, Compton et al, 2005, Alegria et al, 2013) and in our sample in specific, has been widely associated with various substance use disorders, including that for MA (Kleinman et al, 1990, Goldstein et al, 2007, Glasner-Edwards et al, 2010, Howard et al, 2010, Yang et al, 2014), especially in institutional settings (Regier et al, 1990). Moreover, substance use in individuals with ASPD was also found to correlate with greater substance-related problems compared to those without ASPD (Westermeyer and Thuras, 2005, Goldstein et al, 2007).…”

Section: Discussionmentioning

confidence: 60%

Sex Differences in Methamphetamine Use and Dependence in a Thai Treatment Center

Rungnirundorn

Verachai

Gelernter

et al. 2017

Journal of Addiction Medicine

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Background and Objective Males and females who use methamphetamine (MA) differ in socio-demographics, MA diagnoses, co-morbidities, and brain activity. The objective of this study was to investigate sex differences in the characteristics of MA use and dependence in patients at a Thai substance treatment center. Methods Demographic, MA use, and diagnostic data for 782 MA users were obtained by using the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA), Thai version. Categorical comparisons of males (n=413, 53%) and females (n=369, 47%) were made by chi-square test. Factors significantly differentiating men and women with respect to MA dependence were identified by logistic regression analysis controlling for demographic, diagnostic, and MA use variables. Results Males admitted to residential drug treatment for MA use had an earlier age of onset for both MA use (17.7±4.1 vs. 19.7±6.2 years, t=-5.3, p<0.001) and dependence (20.4±5.2 vs. 22.2±6.4 years, t=-3.6, p<0.001). Females were more likely than males to be MA dependent (79% vs. 60%, χ21=33.7, p<0.001), and to experience MA withdrawal (65.3% vs. 48.9%, χ21=21.4, p<0.001), withdrawal related hypersomnia (77.2% vs. 64.8%, χ21=14.5, p<0.001), fatigue (77.5% vs. 70.3%, χ21=5.2, p=0.02) and psychomotor retardation (64.5% vs. 57.0%, χ21=4.5, p=0.03). Similarly, females had heavier (e.g., largest daily amount (χ21=12.4, p<0.001), more frequent (χ21 =5.1, p=0.02)) and greater lifetime episodes of MA use (χ21=24.1, p<0.001) than males. After controlling for such variables by logistic regression, being female remained a significant factor influencing the occurrence of MA dependence (OR=2.7, 95% CI=1.8-4.1, p<0.001). Shared associated factors (or comorbidities) for MA dependence in both sexes included nicotine dependence (in males; OR=4.1, 95% CI=2.4-7.0, p<0.001 and in females; OR=2.4, 95% CI=1.3-4.4, p=0.007), greater lifetime episodes of MA use (in males; OR=3.5, 95% CI=1.9-6.4, p<0.001 and in females; OR=5.9, 95% CI=3.1-11.4, p<0.001) and more frequent use (in males; OR=5.1, 95% CI=2.8-9.1, p<0.001 and in females; OR=3.6, 95% CI=1.9-6.9, p<0.001). Comorbid antisocial personality disorder predicted MA dependence in males only (OR=3.7, 95% CI=1.6-8.6, p=0.002). Conclusions The current study highlights both common (e.g., nicotine dependence and severity of MA use) and sex-specific differences (e.g., MA use/dependence characteristics and comorbidities), including sex itself, with respect to MA dependence in a Thai treatment cohort.

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“…We recruited a purposive sample of participants with drug dependence from drug users incarcerated in the Hunan Xinkaipu Compulsory Isolated Drug Rehabilitation Center (XCIR) located in Changsha, China. This is a compulsory rehabilitation institution for males only, which accommodates over 1,000 individuals who engage in drug use [ 24 ]. Recruitment was performed by a psychological counselor working at the XCIR, who invited individuals that were potentially eligible for the study to participate.…”

Section: Methodsmentioning

confidence: 99%

From Abstinence to Relapse: A Preliminary Qualitative Study of Drug Users in a Compulsory Drug Rehabilitation Center in Changsha, China

et al. 2015

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BackgroundRelapse among abstinent drug users is normal. Several factors are related to relapse, but it remains unclear what individuals’ actual life circumstances are during periods of abstinence, and how these circumstances facilitate or prevent relapse.ObjectiveTo illuminate drug users’ experiences during abstinence periods and explore the real-life catalysts and inhibitors contributing to drug use relapse.MethodQualitative in-depth interviews were conducted with 20 drug users recruited from a compulsory isolated drug rehabilitation center in Changsha. The interviews were guided by open-ended questions on individuals’ experiences in drug use initiation, getting addicted, treatment history, social environment, abstinence, and relapse. Participants were also encouraged to share their own stories. Interviews were digitally recorded and fully transcribed. The data of 18 participants who reported abstinence experiences before admission were included in the analyses. The data were analyzed using a thematic analysis with inductive hand coding to derive themes.ResultsMost drug users were able to successfully abstain from drugs. During abstinence, their lives were congested with challenges, such as adverse socioeconomic conditions, poor family/social support, interpersonal conflicts, and stigma and discrimination, all of which kept them excluded from mainstream society. Furthermore, the police’s system of ID card registration, which identifies individuals as drug users, worsened already grave situations. Relapse triggers reported by the participants focused mainly on negative feelings, interpersonal conflicts, and stressful events. Craving was experienced but not perceived as a relapse trigger by most participants.ConclusionsThis study of in-depth interview with drug users found evidence of situations and environments they live during abstinence appear rather disadvantaged, making it extremely difficult for them to remain abstinent. Comprehensive programs on relapse prevention that acknowledge these disadvantages are implicated.

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Gender differences in prevalence and correlates of antisocial personality disorder among heroin dependent users in compulsory isolation treatment in China

Cited by 9 publications

References 32 publications

Prevalence Rates of Personality Disorder and Its Association With Methamphetamine Dependence in Compulsory Treatment Facilities in China

Prevalence Rates of Personality Disorder and Its Association With Methamphetamine Dependence in Compulsory Treatment Facilities in China

Sex Differences in Methamphetamine Use and Dependence in a Thai Treatment Center

From Abstinence to Relapse: A Preliminary Qualitative Study of Drug Users in a Compulsory Drug Rehabilitation Center in Changsha, China

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