The increasing use of, and dependence on, Information Technology (IT) to support operational teaching, research, and management activities in Higher Education Institutions (HEI)—mainly due to their multi-unit organizational structure—have evidenced the need of encouraging managers to focus more on IT Governance (ITG) effectiveness, which has been an issue for many of these institutions. In this sense, we aim to develop a specific ITG model for Higher Education Institutions, by following the methodological principles of Design Science Research (DSR). The model was developed based on a robust theoretical basis that took into account different approaches substantiated by both the alignment of good practices and ITG focus areas as well as addressing the current ITG context of the Brazilian higher education institutions. The validation of the ITG model was based on its presentation to members of the IT Steering Committee of a Brazilian HEI, who confirmed its usefulness and applicability.