Gene expression of leucocytes in vaccinated Japanese flounder (Paralichthys olivaceus) during the course of experimental infection with Edwardsiella tarda

Molecular profiling of the gilthead sea bream (Sparus aurata L.) response to chronic exposure to the myxosporean parasite Enteromyxum leei

“…In salmonids, several studies have focused on the identification of molecular biomarkers in response to bacterial (Rise et al, 2004;Ewart et al, 2005;Baerwald et al, 2008), viral (Jorgensen et al, 2008;MacKenzie et al, 2008), fungal (Roberge et al, 2007) or parasitic infections (Morrison et al, 2006;Skugor et al, 2008;Wynne et al, 2008aWynne et al, , 2008b. The immune response of channel and blue catfish to bacterial (Peatman et al, 2007(Peatman et al, , 2008 and that of Japanese flounder to bacterial (Matsuyama et al, 2007a), 4 viral (Byon et al, 2005(Byon et al, , 2006, and parasitic (Matsuyama et al, 2007b) infections have also been studied.…”

Microarray analyses of gene expression in Japanese flounder Paralichthys olivaceus leucocytes during monogenean parasite Neoheterobothrium hirame infection

“…Such genes identified in this study were the immunoglobulin heavy chain, immunoglobulin light chain and unknown genes coded as WF12-18R and B613. Immunoglobulin heavy chain and light chain coding genes were up-regulated upon Neoheterobothrium hirame infection (this study), but were down-regulated upon Edwardsiella tarda infection (Matsuyama et al 2006). In contrast, unknown genes WF12-18R and B613 were down-regulated upon N. hirame infection, but were up-regulated upon E. tarda infection.…”

“…Comparing with the previous study that analyzed the gene expression of PBL after infection with Edwardsiella tarda (Matsuyama et al 2006), some genes were commonly up-regulated with the infection of Neoheterobothrium hirame and E. tarda. These genes included MMP-9, MMP-13, CD20 receptor and unknown genes coded as LB3 (8) and WE8-18R.…”

“…Resale or republication not permitted without written consent of the publisher siella tarda infection (Matsuyama et al 2006) in Japanese flounder Paralichthys olivaceus. In this study, we chose Neoheterobothrium hirame as an example of a monogenean infection in order to select the genes that could be utilized as infection-markers.…”

Molecular cloning and expression of PoIR2, a novel gene involved in immune response in Japanese flounder (Paralichthys olivaceus)

“…Both types of immunity are controlled through the network system by intra-and extra-cellular factors (Banyer et al, 2000;Hawiger, 2001). Many molecular tools were used to characterize the immune system of Japanese flounder, and a lot of immune-related genes were identified, such as IFN, IL, TNF, MHC, AMP and many function-un-known genes (Nam et al, 2000;Kono and Sakai, 2001;Kurobe et al, 2005;Aoki and Hirono, 2006;Matsuyama et al, 2007;Dumrongphol et al, 2009).…”