Gene frequencies of ABO and Rh(D) blood group alleles in Lagos, South-West Nigeria

Iyiola, Oluyinka A.; Igunnugbemi, O. O; Bello, O.G.

doi:10.1016/j.ejmhg.2011.08.006

Cited by 25 publications

(33 citation statements)

References 19 publications

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“…In Guinean population, 22%, 24%, 5% and 49% belongs respectively to blood groups A, B, AB and O (Loua, Lamah, Haba, & Camara, ). In Nigerian populations, the frequencies of phenotypes A, B, AB, O, RHD+, RHD− varied respectively between 20.5%–23.1%, 20.7%–21.3%, 1.6%–2.7%, 52.9%–57.2%, 94.8%–97% and 3%–5.2% (Iyiola, Igunnugbemi, & Bello, ; Mohammed et al, ).…”

Section: Introductionmentioning

confidence: 99%

Distribution of ABO and RHD blood group antigens in blood donors in Burkina Faso

Sawadogo

Nébié

Millogo³

et al. 2018

Int J Immunogenetics

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Geographical distribution of ABO and RHD antigens is important for blood transfusion services and population genetics studies. There are few data on this topic in Burkina Faso, a multi‐ethnic country. Our study aims at reporting phenotypic and allelic frequencies of ABO and RHD blood groups among voluntary blood donors from various ethnical regions of Burkina Faso. We conducted a cross‐sectional study including 81,486 blood donors. ABO allelic frequencies were determined using the Bernstein method. Differences in phenotypic distribution of blood groups were assessed using the chi‐square test; a p value <0.05 being considered as statistically significant. We noticed that O+>B+>A+>AB+>O‐>B‐>A‐>AB‐ in our population. Phenotypic frequencies of blood groups A, B, O and AB were respectively 22.54%, 28.56%, 43.30% and 5.60%. RHD+was 92.24%. The allelic frequencies of A, B, O and D were respectively 0.1524; 0.1887; 0.6590 and 0.7214. We noticed statistical differences (p < 0.05) between these administrative regions which corresponded roughly to some natural ethnic areas. Indeed, the phenotype O was more frequent in the Central‐west, Central and East regions corresponding to “Mossi,” “Gourounsi,” “Gourmantché” areas while the phenotype A and AB were more reported in “Boucle du mouhoun” and “Hauts‐Bassins” regions where we have “Bwaba” and “Bobo.” The phenotype O negative was less frequent in “Bwaba.” Our study provides interesting information to blood services that will allow them to better refine their donor recruitment strategies.

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Section: Introductionmentioning

confidence: 99%

Distribution of ABO and RHD blood group antigens in blood donors in Burkina Faso

Sawadogo

Nébié

Millogo³

et al. 2018

Int J Immunogenetics

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“…Rh phenotypes studied in South West Nigeria resulted in a ratio of 97:3 for positive and negative cases. 7 These two studies reflect difference in the phenotypic distribution in two different sites in the same country although Rh + cases are much higher than Rh -in both cases. Eweidah et al (2011) found that Rh + subjects were over 10 times more than Rh -subjects in 4 cities of Al-Jouf province in Saudi Arabia.…”

Section: Resultsmentioning

confidence: 95%

“…A number of blood group system have so far been discovered in man of which ABO blood type polymorphism and Rhesus (Rh) blood grouping received highest clinical, anthropological, immunological and biological attention. 3,5,7,4 Karl Landsteiner (1900) and his pupil Von Decastello and Sturli (1902) in Austria demonstrated that four blood group phenotypes (A, B, AB and O) exist in human being formed out of three polymorphic alleles (A,B and O). This happens according to the presence or absence of red blood cell (RBC) surface antigen viz.…”

Section: Introductionmentioning

confidence: 99%

“…Both ABO and Rh data are inevitably needed in blood transfusion and organ transplantation. 5,7 Apart from these, population data on ABO gene frequency can be used to estimate genetic distance between sub-populations 3 , to study genetic and ethnic diversity of human population 5 ,to know genetic relationship among different populations by examining the geographical distribution of gene frequencies 10 , to determine migration pattern and origin of human race 4 , to manufacture and marketing of race-specific drug 12 which led to develop a subject like ethno-medicine and to resolve issues related to parentage.…”

Section: Introductionmentioning

confidence: 99%

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Distribution pattern of ABO and Rh blood groups and their allelic frequencies among different ethnic groups in Malaysia

2014

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Background: The experiment involved 4 different racial populations such as Malay (M), Chinese (C), Indian Tamil (I) and confounded population termed as Others (O) from 13 states and 1 federal territory in Malaysia.Methods: A total of 1101 students in Universiti Malaysia Kelantan were surveyed for ABO blood type and Rh factor.Results: Phenotypic frequencies were 0.24, 0.27, 0.09 and 0.40 in M; 0.26, 0.21, 0.06 and 0.38 in C; 0.27, 0.31, 0.09 and 0.33 in I and 0.11, 0.29, 0.09 and 0.51 in O for A, B, AB and O blood group, respectively. Rh+ve cases were found to be abundant and distributed as 0.92, 0.94, 0.89 and 0.79 among M, C, I and O race, respectively. Allele frequencies of IA, IB and i were estimated at 0.17, 0.20 and 0.63 in M; 0.19, 0.16 and 0.65 in C; 0.20, 0.23 and 0.57 in O, respectively. Insignificant χ2 (0.05, 2 = 5.991) interprets that ABO allele frequencies exist in Hardy-Weinberg equilibrium in all races. However, high magnitude of χ2 in M (5.463) signifies continued admixture in the M genetic population or the population is less stable than C and I. C and I are in more stabilized condition in this regard that might be because of closed breeding within them.Conclusion: Results of this study might be useful to blood transfusion services in Malaysia apart from human population geneticists. DOI: http://dx.doi.org/10.3126/ajms.v6i4.11257 Asian Journal of Medical Sciences Vol.6(4) 2015 25-29

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“…Our Study Black [19] RDC [39] India [40] White [19] American Indian [19] Nigeria [41] Algeria [26] Zambie [42] Moroco [ Rh3 and Rh2 IFMEs are to be feared in this population.…”

Section: Rhesusmentioning

confidence: 99%

Blood Group Cartography (ABO, RHESUS, KELL and DUFFY) and Hemogram of Icteric Newborn in Sendwe Hospital, Lubumbashi/D.R.C

Kalenga¹,

Davidson²,

Serge³

et al. 2020

JPP

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Background: Allo immunization jaundice is a common cause of neonatal jaundice. According to racial group the concerned blood group may not be the same. In our Country people are exposed to high transfusionnal risk because of malaria and sicklanemia and the blood group research in laboratory include only ABO/D. Objective: Our objective was to establish a blood group cartography of this icteric newborn population and their mother; the frequency of rare blood group and the compatibility level between mother and newborn. Our interest was also to study hemogram of this population. Methodology: We studied blood group ABO/D; RH/Kell and Duffy of 56 newborn whom developped an indirect bilirubin and their mothers. We performed bilrubin level and hemogram. Results: The frequency of icteric newborn was 17.17%. The mother blood mapping was O (60.71%), RhD positive (83.9%), C negative (91.07%) E negative (89.29%) c positive (91.07%), epositive (92.86%), kell negative (100%) and duffy null (100%). The most common phenotype was ccDee (67.9%) Neonatal was ex aequo O and B (37.50% respectivly), RH D positive (87.50%), RhC negative (87.50%), Rh E negative (89.29%), Rhc positive (96.43%), Rh e positive (96.43%), Kell negative (98.21%) and duffy null (100%), 75% of newborn had the phenotype ccDee. We noticed 9% of extremely rare blood group in maternal population. Mean level of bilirubin was 11.48 mg% at H48. Analyse of hemogram reveal a normocytic and normochromic anemia. Conclusions: Mapping blood group of this population reveal the importance of extended blood grouping in icteric newborn and their mother. Our population presents a blood group that is widely open to allo immunization in all studied blood group.

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Gene frequencies of ABO and Rh(D) blood group alleles in Lagos, South-West Nigeria

Cited by 25 publications

References 19 publications

Distribution of ABO and RHD blood group antigens in blood donors in Burkina Faso

Distribution of ABO and RHD blood group antigens in blood donors in Burkina Faso

Distribution pattern of ABO and Rh blood groups and their allelic frequencies among different ethnic groups in Malaysia

Blood Group Cartography (ABO, RHESUS, KELL and DUFFY) and Hemogram of Icteric Newborn in Sendwe Hospital, Lubumbashi/D.R.C

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