General obesity, abdominal adiposity, and the risk of incident hypertension—From anthropometry to modern imaging techniques

Georgianos, Panagiotis I.; Zebekakis, Pantelis

doi:10.1111/jch.13377

Cited by 7 publications

(8 citation statements)

References 20 publications

(44 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…WAT is responsible for storing fat as energy. It stores energy in the form of triglycerides and causes obesity and multiple metabolic diseases ( 34 ). It also releases energy into the body in the form of free fatty acids and glycerol ( 35 ).…”

Section: Bat-secreted Factors — Adipokines Improve Metabolic Healthmentioning

confidence: 99%

Brown Adipose Tissue and Novel Management Strategies for Polycystic Ovary Syndrome Therapy

Zhang

et al. 2022

Front. Endocrinol.

View full text Add to dashboard Cite

Brown adipose tissue (BAT), a unique tissue, plays a key role in metabolism and energy expenditure through adaptive nonshivering thermogenesis. It has recently become a therapeutic target in the treatment of obesity and metabolic diseases. The thermogenic effect of BAT occurs through uncoupling protein-1 by uncoupling adenosine triphosphate (ATP) synthesis from energy substrate oxidation. The review discusses the recent developments and progress associated with the biology, function, and activation of BAT, with a focus on its therapeutic potential for the treatment of polycystic ovary syndrome (PCOS). The endocrine activity of brown adipocytes affects the energy balance and homeostasis of glucose and lipids, thereby affecting the association of BAT activity and the metabolic profile. PCOS is a complex reproductive and metabolic disorder of reproductive-age women. Functional abnormalities of adipose tissue (AT) have been reported in patients with PCOS. Numerous studies have shown that BAT could regulate the features of PCOS and that increases in BAT mass or activity were effective in the treatment of PCOS through approaches including cold stimulation, BAT transplantation and compound activation in various animal models. Therefore, BAT may be used as a novel management strategy for the patients with PCOS to improve women’s health clinically. It is highly important to identify key brown adipokines for the discovery and development of novel candidates to establish an efficacious therapeutic strategy for patients with PCOS in the future.

show abstract

Section: Bat-secreted Factors — Adipokines Improve Metabolic Healthmentioning

confidence: 99%

Brown Adipose Tissue and Novel Management Strategies for Polycystic Ovary Syndrome Therapy

Zhang

et al. 2022

Front. Endocrinol.

View full text Add to dashboard Cite

show abstract

“…Em busca de maior praticidade, há um interesse crescente na clínica de utilizar medidas antropométricas para identificar indivíduos com risco de doenças cardiometabólicas (CARVALHO et al, 2021;IMAHORI et al, 2020) ou na estimativa da gordura corporal (VILHENA et al, 2019;SANTOS, 2017;MATERKO et al, 2010), pois são técnicas simples e quando combinados podem prever com maior precisão a gordura abdominal (PASANTA et al, 2021;GEORGIANOS;ZEBEKAKIS, 2018).…”

Section: Abstract -unclassified

Modelo De Predição Da Gordura Visceral Relativa Baseado Nas Características Antropométricas De Mulheres Do Programa Do Núcleo De Apoio Saúde Da Família (Nasf) Residentes Em Macapá, Ap

Azevedo¹,

Conceição²,

Dias³

et al. 2022

TeS

View full text Add to dashboard Cite

show abstract

“…The prevalence of hypertension among adults is >25% in 2020 and has been predicted to be up to 29% by 2025 worldwide [2]. The increase in the prevalence of hypertension is parallel to that in the prevalence of obesity [3,4]. Following rapid economic and social changes, the most notable changes are sharp shift in diet accompanied by lack of physical activity in China [5,6].…”

Section: Introductionmentioning

confidence: 99%

“…It was reported that overweight could exacerbate the effect of famine exposure on the prevalence of hypertension [9]. In addition, obesity patterns including general and abdominal obesity and their combination have different effects on the risk of hypertension [4,12]. However, up to now, little is known on whether there was interaction between obesity patterns and famine exposure on the incidence of hypertension.…”

Section: Introductionmentioning

confidence: 99%

Exposure to Chinese Famine in the Early Life, Adulthood Obesity Patterns, and the Incidence of Hypertension: A 22-Year Cohort Study

et al. 2021

View full text Add to dashboard Cite

Introduction: Little is known regarding the joint associations of famine exposure and obesity patterns with the incidence of hypertension. Methods: We defined famine exposure cohorts as follows: nonexposure (born between 1962 and 1965), fetal life exposure (born between 1959 and 1961), early childhood exposure (born between 1956 and 1958), midchildhood exposure (born between 1953 and 1955), and late childhood exposure (born between 1949 and 1952). Obesity patterns were defined as follows: G−/A−: subjects without neither general obesity nor abdominal obesity; G+/A− or G−/A+: subjects with either general obesity or abdominal obesity; G+/A+: subjects with both general obesity and abdominal obesity. Hypertension was defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg or current treatment with antihypertensive medications. Results: There were 5,235 individuals participating in this study. In the subjects with general or abdominal obesity, famine exposure was associated with a lower risk of hypertension. In males with G−/A−, famine exposures in the midchildhood (p = 0.048; HR: 0.700; HR 95% CI: 0.491–0.998) and late childhood (p = 0.002; HR: 0.560; HR 95% CI: 0.374–0.840) were associated with a lower incidence of hypertension. Conclusion: The coexistence of famine exposure and obesity patterns was associated with the incidence of hypertension.

show abstract

General obesity, abdominal adiposity, and the risk of incident hypertension—From anthropometry to modern imaging techniques

Cited by 7 publications

References 20 publications

Brown Adipose Tissue and Novel Management Strategies for Polycystic Ovary Syndrome Therapy

Brown Adipose Tissue and Novel Management Strategies for Polycystic Ovary Syndrome Therapy

Modelo De Predição Da Gordura Visceral Relativa Baseado Nas Características Antropométricas De Mulheres Do Programa Do Núcleo De Apoio Saúde Da Família (Nasf) Residentes Em Macapá, Ap

Exposure to Chinese Famine in the Early Life, Adulthood Obesity Patterns, and the Incidence of Hypertension: A 22-Year Cohort Study

Contact Info

Product

Resources

About