The work is devoted to the study of the adaptive features of the histological structure of the liver of some representatives of the hare order. The material for the study was organocomplexes from clinically healthy productive rabbits, decorative rabbits and white hare. Research work was carried out at the Department of Anatomy and Physiology of the Federal State Budgetary Educational Institution of Higher Education of the State Agrarian University of the Northern Trans-Urals. Conducted morphometric studies and selected material for morphological and histological studies. The liver of the studied species of the order Lagomorphs has a convex parietal and slightly concave visceral surface. The right and left lobes of the liver are divided into lateral and medial parts. In a productive rabbit and a decorative rabbit, the lateral right lobe is shorter than the lateral left lobe, and in the white hare, both of these are short. The square share of all is an elongated quadrangular shape. Caudate and mastoid processes are small. The gallbladder lies between the right lateral and right medial lobes and does not extend beyond the ventral edge of the liver. Histological studies were carried out according to generally accepted methods. In all species of the order of lagomorphs, formed triads were observed located on the border between the lobules. Hepatocytes form hepatic laminae. Trabeculae and loose fibrous connective tissue are not expressed. Analyzing the obtained histological data, we can say that the adaptive features will include: in rabbits bred under industrial conditions - an increased area of hepatocytes (376.29±22.95 µm2) and nuclei (52.44±4.51 µm2), a decrease in NCR 0.16±0.007; in ornamental rabbits - a decrease in the area of hepatocytes (38.32±1.77 µm2) and nuclei (7.06±0.59 µm2), but the average value of the Nuclear-Cytoplasmic Ratio is 0.42±0.01; in the hare - the average values of the area of hepatocytes (260.79±15.88 µm2) and nuclei (41.58±1.32 µm2), NCR 0.4±0.01. These features indicate significant differences in the nutrition and maintenance of these animals, as well as various adaptation processes.