Generalised infantile myofibromatosis with intracranial involvement: imaging findings in a newborn

Spadola, Luca; Anooshiravani, Mehrak; Sayegh, Yasmine; Jequier, Sigrid; Hanquinet, Sylviane

doi:10.1007/s00247-002-0758-8

Cited by 34 publications

(24 citation statements)

References 11 publications

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“…The center of a myofibroma may appear mildly hyperintense on T1-weighted images. Enhancement often is intense, and these lesions occasionally demonstrate a targetlike enhancement pattern (8,37).…”

Section: Myofibromamentioning

confidence: 98%

Soft Tissue Tumors of the Head and Neck: Imaging-based Review of the WHO Classification

Razek

Huang²

2011

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The World Health Organization (WHO) system for defining and classifying soft tissue tumors is usually applied to lesions that occur in the trunk and extremities, but it also provides an excellent framework for characterizing nonepithelial extraskeletal tumors of the head and neck. Although nonepithelial extraskeletal tumors are in the minority among head and neck lesions, they are by no means rare. The WHO classification system recognizes nine major types based on histologic differentiation: adipocytic, fibroblastic or myofibroblastic, fibrohistiocytic, smooth muscle, skeletal muscle, vascular, pericytic, and chondro-osseous tumors, as well as soft tissue tumors of uncertain differentiation. Tumors of each histologic type may be further subclassified on the basis of their biologic behavior as benign, intermediate (ie, having malignant potential), or malignant. Imaging plays an important role in the noninvasive diagnosis and characterization of nonepithelial soft tissue tumors of the head and neck, providing clues about tumor grade, composition, extent, and involvement of adjacent structures. Although the imaging characteristics of many such tumors are nonspecific, consideration of the clinical history in concert with the imaging findings may help limit the differential diagnosis or even allow reliable diagnosis of some of these tumors.

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Section: Myofibromamentioning

confidence: 98%

Soft Tissue Tumors of the Head and Neck: Imaging-based Review of the WHO Classification

Razek

Huang²

2011

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129

108

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“…Solitary IM in the primary visceral organs is extremely rare and is thus quite difficult to prognosticate. On the other hand, multicentric IM of the primary visceral organs has been reported in a substantial number of cases, sometimes with fatal outcome [6][7][8]. Solitary IM recurs in less than 10% of cases after excision, and in some cases unresected tumors have been reported to spontaneously regress [9].…”

Section: Discussionmentioning

confidence: 96%

Congenital occurrence of solitary infantile myofibromatosis of the spleen

Izumi

Ohno

Kamitamari

et al. 2008

Journal of Pediatric Surgery

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Infantile myofibromatosis (IM) is a rare soft tissue tumor of infancy and childhood. We report the case of a newborn girl with an abdominal tumor discovered at 32 weeks of gestation by fetal ultrasound. She underwent a laparotomy for an unexplained abdominal mass 20 days after birth. The tumor originated from the spleen and was removed by splenectomy. There were no other abnormal findings on diagnostic modalities. Based on the histological examinations, the tumor was diagnosed as an IM. Although extremely rare during the neonatal period, solitary type IM should be considered as a differential diagnosis of the splenic tumor.

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“…In that series, two of the cases were mandibular, three involved the gingivae, two were lingual and two were palatal (Montgomery et al, 2000). Other areas can be affected, including intrabony, internal organs or intracranial locations (Spandola et al, 2002).…”

Section: Discussionmentioning

confidence: 98%