Generalized pustular psoriasis associated with Turner syndrome and dilated cardiomyopathy

Ito, Michiko; Maejima, Yasuhiro; Okazaki, Shuzo; Isobe, Mitsuaki; Saeki, Hidehisa

doi:10.1111/1346-8138.13290

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…The mutation analysis for IL36RN, AP1S3 and CARD14 was negative, and this may explain why the GPP was relatively mild. A literature search identified six other cases of GPP associated with Turner syndrome . All these cases were mild and responsive to treatment, as in our case.…”

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confidence: 53%

A case of pustular psoriasis possibly precipitated by periodic oestrogen/gestagen therapy for Turner syndrome

et al. 2019

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confidence: 53%

A case of pustular psoriasis possibly precipitated by periodic oestrogen/gestagen therapy for Turner syndrome

et al. 2019

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“…Moreover, it is also possible that patients who suffer from TS and psoriasis are at an even greater risk of developing or worsening already present cardiometabolic comorbidities, which calls for greater awareness to risk assess and manage cardiovascular disease and metabolic syndrome in this patient population. Ito et al reported a case of a patient with TS who was suffering from pustular psoriasis and subsequently developed dilated cardiomyopathy hypothesizing that chronic inflammation may be a predisposing factor for dilated cardiomyopathy in this patient population [18]. Davenport proposed management approaches to TS patients [19]; considering our patient suffered from TS and psoriasis, these approaches may have to be enhanced.…”

Section: Discussionmentioning

confidence: 95%

A Case Report of a Patient with Turner Syndrome, Multiple Comorbidities, and Pustular Psoriasis: Correlation or Coincidence?

Egger

Lev‐Tov

Stojadinović

2020

Case Reports in Dermatological Medicine

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Turner syndrome (TS) is one of the most common chromosomal abnormalities. Patients with TS are at an increased risk for the development of metabolic syndrome, hypertension (HTN), diabetes mellitus type II (DM2), hyperlipidemia (HLD), obesity, and cardiovascular disease. The association between psoriasis and the aforementioned conditions including metabolic syndrome, HTN, HLD, obesity, and cardiovascular disease has also been established. Although the mechanism for heightened risk in TS patients is yet to be elucidated, patients suffering from TS and cardiometabolic diseases are likely to be at an even higher risk for developing psoriasis than patients suffering from TS alone. We present a case of a 53-year-old Hispanic woman with a mosaic TS and multiple comorbidities who presented with pustular psoriasis. For this patient, management can be challenging considering her numerous medical comorbidities and the presence of both TS and psoriasis.

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Dermatologic Conditions in Turner Syndrome

Haskin

Lowenstein

2020

Turner Syndrome

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Generalized pustular psoriasis associated with Turner syndrome and dilated cardiomyopathy

Cited by 3 publications

References 5 publications

A case of pustular psoriasis possibly precipitated by periodic oestrogen/gestagen therapy for Turner syndrome

A case of pustular psoriasis possibly precipitated by periodic oestrogen/gestagen therapy for Turner syndrome

A Case Report of a Patient with Turner Syndrome, Multiple Comorbidities, and Pustular Psoriasis: Correlation or Coincidence?

Dermatologic Conditions in Turner Syndrome

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