The increasing complexity of cyber-physical systems (CPSs) makes their design, development and operation extremely challenging. Due to the nature of CPS that involves many heterogeneous components, which are often designed and developed by organizations belonging to different engineering domains, it is difficult to manage, trace and verify their properties, requirements and constraints throughout their lifecycle by using classical techniques. In this context, the paper presents an integrated solution to formally define system requirements and automate their verification through simulation. The solution is based on the FOrmal Requirements Modeling Language and the Modelica language. The solution is exemplified through two case studies concerning a Trailing-Edge High-Lift system and a Heating, Ventilation and Air Conditioning system.