Me mbers of today's technologically oriented societies have increasingly diminished contact with natural form. This is probably due to a combination of reduced contact with real nature and exposure to architectural settings devoid of references to natural form (e.g. minimalist architecture). Humans, however, evolved in natural environments, and there is reason to believe that the human brain is adapted to processing natural settings and objects. The central aim of this article is to make some suggestions pertaining to the field of architecture that may help in overcoming the discrepancy between the workings of the brain and modern living environments.In the first part of this article, I present evidence that humans are endowed with a cognitive system specially dedicated to natural information. The existence of so-called biophilic responses suggests that this system is linked to neural areas dedicated to causing emotional reactions. The subsequent parts consider how these neural assemblies can be stimulated by biomorphic architecture, which shares essential geometric features with natural objects. After a presentation of examples, the final sections discuss how such architecture can enrich the human relationship to the built environment.