Genes Associated with Fatty Acid Composition of Beef

Mannen, Hideyuki

doi:10.3136/fstr.18.1

Cited by 8 publications

(8 citation statements)

References 32 publications

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“…Our data indicated that the genotype of sire A might be homozygous for the Ala allele and other sires might have more than one Ala allele. SCD c.878T>C (p.Val293Ala) has been reported to improve MUFA content in Japanese Black, Fleckvieh, Hanwoo, and Holstein cattle (Barton et al 2010;Oh et al 2011;Mannen 2012). Therefore, this SNP may also have a desirable effect on MUFA content of the Kumamoto sub-breed, and this effect may be the cause of the deviation from the HWE.…”

Section: Resultsmentioning

confidence: 99%

Elucidating genetic characteristics of the Kumamoto sub-breed of Japanese Brown cattle with DNA markers for economically important traits

Kimura

Kurihara

Inoue

et al. 2021

The Journal of Animal Genetics

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Wagyu, a variety of beef cattle of Japanese origin, includes four genetically distinct breeds: Japanese Black, Japanese Brown, Japanese Shorthorn, and Japanese Polled (Gotoh et al. 2018). Japanese Brown cattle, raised mainly in the Kumamoto and Kochi prefectures, are the second most popular breed among the Wagyu breeds. The coat color patterns of the sub-breeds found in these two prefectures are apparently different, suggesting genetic isolation between

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Section: Resultsmentioning

confidence: 99%

Elucidating genetic characteristics of the Kumamoto sub-breed of Japanese Brown cattle with DNA markers for economically important traits

Kimura

Kurihara

Inoue

et al. 2021

The Journal of Animal Genetics

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“…Previous study reported that the CAST, CAPN, and SCD genes are known as genetic markers used for meat quality (Cassar-Malek and Picard 2016), especially for tenderness and marbling scores (Kök and Atalay 2018), as well as fatty acids (Mannen 2012;Sevane et al 2013). Lozano et al (2016) reported that SNP CAPN316 and CAPN475 significantly affected the meat tenderness, while SNP CAST-T1 did not affect the commercial beef cattle and Sevane et al (2013) reported that SNP g.10329T>C exon 5 significantly affected the fatty acids in European cattle breeds.…”

Section: Discussionmentioning

confidence: 99%

Investigating new SNPs of CAST, CAPN and SCD genes in 5’UTR of Bali cattle

et al. 2020

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Abstract. Jakaria, Ulum MF, Lestari D, Akwila S, Sihite DEWT, Priyanto R, Muladno, Sumantri C. 2020. Investigating new SNPs of CAST, CAPN and SCD genes in 5’UTR of Bali cattle. Biodiversitas 21: 2971-2976. The present investigation aims to explore specific SNPs of Bali cattle, focusing mainly on CAST, CAPN, and SCD genes in 5'UTR. DNA of Bali cattle (25 individuals) from Breeding Centre of Bali cattle in Bali Province, Indonesia, were extracted according to the protocol of GenAID. Amplification of the CAST, CAPN, and SCD genes were designed using the Primer3 program based on reference sequences (access numbers AH014526.2, AH009246.3, and AY241932). Furthermore, the PCR product was sequenced through forward primer sequencing. The data sequence results were analyzed using the Bioedit, MEGA7, Popgen 3.2, and DnaSP6 V6 programs. The results showed that SNPs were detected at g.921C>T and g.922T>G in 5'UTR for the CAST gene between the reference of GenBank AH014526.2 and Bali cattle, but it was monomorphic within the population. The high polymorphism of SNPs was found in g.232G>T for the CAPN gene and g.134A>del for the SCD gene. However, the SNP g.246C>del SCD gene was detected as monomorphic in this region. Moreover, this result shows that low nucleotide diversities (Pi) for CAST, CAPN, and SCD genes in 5'UTR of Bali cattle were 0.00422, 0.00632, and 0.00449, respectively. This finding was important for developing marker-assisted selection (MAS) to improve the meat quality of Bali cattle.

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“…This is followed by an elongation step, after which the FADS1 catalyzes the conversion of eicosatetraenoic acid (C20:4 n ‐3) and dihomo‐ γ ‐linolenic acid (C20:3 n ‐6) into C20:5 n ‐3 and C20:4 n ‐6, respectively. The FABP4 belongs to a cytoplasmic protein family involved in intracellular free fatty acid transport and metabolism . Stearoyl‐CoA desaturase ( SCD1 ), also known as Δ 9 ‐desaturase, plays a key role in the conversion of SFAs into MUFAs as well as in the PUFA production: C18:2 c 9, t 11 from C18:1 t 11 and C18:2 t 7, c 9 from C18:1 t 7 …”

Section: Strategies To Produce Healthier Ruminant Meatmentioning

confidence: 93%

“…The FABP4 belongs to a cytoplasmic protein family involved in intracellular free fatty acid transport and metabolism. 93 Stearoyl-CoA desaturase (SCD1), also known as Δ 9 -desaturase, plays a key role in the conversion of SFAs into MUFAs as well as in the PUFA production: C18:2 c9, t11 from C18:1 t11 and C18:2 t7, c9 from C18:1 t7. 92 Dietary manipulation of FA composition in ruminants is partially mediated through the regulation of lipogenic enzymes expression and this regulation is tissue specific.…”

Section: Strategies To Produce Healthier Ruminant Meatmentioning

confidence: 99%

Impacts of fat from ruminants' meat on cardiovascular health and possible strategies to alter its lipid composition

Vargas‐Bello‐Pérez

Larraín

2017

J Sci Food Agric

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In the last few decades there has been increased consumer interest in the fatty acid (FA) composition of ruminant meat due to its content of saturated FAs, which have been implicated in diseases associated with modern life. However, recent studies have questioned the recommendations to reduce intake of fat, saturated FAs and cholesterol as a means of reducing the risk of cardiovascular disease. Interestingly, ruminant meat has some bioactive lipids such as C18:1t11 and C18:2 c9, t11 which have been reported to have positive effects on human health. In order to improve muscle fat composition from a human health standpoint, oilseeds, plant oils and marine oils can be used in ruminant diets. On the other hand, molecular mechanisms play an important role in the alteration of the FA composition of muscle fat. Genetics offer a wide range of possibilities for improvement of muscle fat composition by identifying different loci underlying the expression of quantitative traits. While significant progress has been made in characterizing the influence of diet on the FA composition of ruminant meat, the use of genetic tools can favor genotypes that could maximize their genetic potential through the diet. © 2016 Society of Chemical Industry.

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Genes Associated with Fatty Acid Composition of Beef

Cited by 8 publications

References 32 publications

Elucidating genetic characteristics of the Kumamoto sub-breed of Japanese Brown cattle with DNA markers for economically important traits

Elucidating genetic characteristics of the Kumamoto sub-breed of Japanese Brown cattle with DNA markers for economically important traits

Investigating new SNPs of CAST, CAPN and SCD genes in 5’UTR of Bali cattle

Impacts of fat from ruminants' meat on cardiovascular health and possible strategies to alter its lipid composition

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