The micro-genetic algorithm (MGA) optimization combined with the finite-difference time-domain (FDTD) method is applied to design a band-notched ultra wide-band (UWB) antenna. A U-type slot on a stepped U-type UWB monopole is used to obtain the band-notched characteristic for 5 GHz wireless local area network (WLAN) band. The measured results show that voltage standing wave ration (VSWR) less than 2 covers 3.1-10.6 GHz operating band and VSWR more than 2 is within 5.150-5.825 GHz notched one with the highest value of 5.6. Agreement among the calculated, HFSS simulated and measured results validates the effectiveness of this MGA-FDTD method, which is efficient for UWB antennas design.