Genetic diversities and phylogenetic analyses of three Chinese main ethnic groups in southwest China: A Y-Chromosomal STR study

Chen, Pengyu; He, Guanglin; Zou, Xing; Zhang, Xin; Li, Jida; Wang, Zhisong; Gao, Hongyan; Luo, Li; Zhang, Zhongqing; Yu, Jian; Han, Yanyan

doi:10.1038/s41598-018-33751-x

Cited by 31 publications

(25 citation statements)

References 59 publications

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“…From the dimensionality reduction analyses discussed above, the genetic relationships between Guangdong She and other Chinese populations were not clarified. In addition, we employed the Y-STR haplotype profiles of 42 Chinese minorities and Guangdong She to assess the population pairwise genetic distances by AMOVA ( Zhu et al, 2005 , 2006a , b , 2008 ; He and Guo, 2013 ; Shan et al, 2014 ; Luo et al, 2015 , 2019 ; Ou et al, 2015 ; Shu et al, 2015 ; Bai et al, 2016a ; Bian et al, 2016 ; Fu et al, 2016 ; Gao et al, 2016 ; Yao et al, 2016 ; Guo et al, 2017 ; Ji et al, 2017 ; Zhao et al, 2017 ; Cao et al, 2018 ; Chen et al, 2018 ; Liu Y. J. et al, 2018 ; Atif et al, 2019 ; Liu et al, 2019 ; Xie et al, 2019 ; Dezhi et al, 2020 ; Feng et al, 2020 ; Song et al, 2020 ; Tang et al, 2020 ). The pairwise R ST and the corresponding p values between Guangdong She and Chinese minority populations from five linguistically different families are displayed in Supplementary Table 7 .…”

Section: Resultsmentioning

confidence: 99%

Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups

Luo

Duan²,

et al. 2021

Front. Genet.

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Guangdong province is situated in the south of China with a population size of 113.46 million. Hakka is officially recognized as a branch of Han Chinese, and She is the official minority group in mainland China. There are approximately 25 million Hakka people who mainly live in the East and North regions of China, while there are only 0.7 million She people. The genetic characterization and forensic parameters of these two groups are poorly defined (She) or still need to be explored (Hakka). In this study, we have genotyped 475 unrelated Guangdong males (260 Hakka and 215 She) with Promega PowerPlex® Y23 System. A total of 176 and 155 different alleles were observed across all 23 Y-STRs for Guangdong Hakka (with a range of allele frequencies from 0.0038 to 0.7423) and Guangdong She (0.0047–0.8605), respectively. The gene diversity ranged from 0.4877 to 0.9671 (Guangdong Hakka) and 0.3277–0.9526 (Guangdong She), while the haplotype diversities were 0.9994 and 0.9939 for Guangdong Hakka and Guangdong She, with discrimination capacity values of 0.8885 and 0.5674, respectively. With reference to geographical and linguistic scales, the phylogenetic analyses showed us that Guangdong Hakka has a close relationship with Southern Han, and the genetic pool of Guangdong Hakka was influenced by surrounding Han populations. The predominant haplogroups of the Guangdong She group were O2-M122 and O2a2a1a2-M7, while Guangdong She clustered with other Tibeto-Burman language-speaking populations (Guizhou Tujia and Hunan Tujia), which shows us that the Guangdong She group is one of the branches of Tibeto-Burman populations and the Huonie dialect of She languages may be a branch of Tibeto-Burman language families.

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Section: Resultsmentioning

confidence: 99%

Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups

Luo

Duan²,

et al. 2021

Front. Genet.

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“…Although Chinese male genetic landscape was revisited by 38,000 17-Y-STR haplotypes study[8], the analysis of population stratification and genetic relationships among Chinese Han and minorities based on only 17 loci may not be accurate enough. Chen at al [41] also investigated the genetic diversity of 98 Qiannan Bouyei, 101 Zunyi Han and 109 Qiandongnan Miao individuals based on 23 Y-STRs loci, all of which located in Guizhou province, but more attention should be still paid in the forensic practices and population genetic applications due to the relatively small sample size.…”

Section: Discussionmentioning

confidence: 99%

Population genetic analysis of 36 Y-chromosomal STRs yields comprehensive insights into the forensic features and phylogenetic relationship of Chinese Tai-Kadai-speaking Bouyei

Luo

Wu²,

Qian

et al. 2019

PLoS ONE

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Male-specifically inherited Y-STRs, harboring the features of haploidy and lack of crossing over, have gained considerable attention in population genetics and forensic investigations. Goldeneye® Y-PLUS kit was a recently developed amplification system focused on the genetic diversity of 36 Y-chromosomal short tandem repeats (Y-STRs) in East Asians. However, no population data and corresponding forensic features were reported in China. Here, 36 Y-STRs were first genotyped in 400 unrelated healthy Tai-Kadai-speaking Bouyei male individuals. A total of 371 alleles and 396 haplotypes could be detected, and the allelic frequencies ranged from 0.0025 to 0.9875. The haplotype diversity, random match probability and discrimination capacity values were 0.9999, 0.0026 and 0.9900, respectively. The gene diversity (GD) of 36 Y-STR loci in the studied group ranged from 0.0248 (DYS645) to 0.9601 (DYS385a/b). Population comparisons between the Guizhou Bouyei and 80 reference groups were performed via the AMOVA, MDS, and phylogenetic relationship reconstruction. The results showed that the population stratification was almost consistent with the geographic distribution and language-family, both among Chinese and worldwide ethnic groups. Our newly genotyped Bouyei samples show a close affinity with other Tai-Kadai-speaking groups in China and Southeast Asia. Our data may provide useful information for paternal lineage in the forensic application and population genetics, as well as evidence for archaeological and historical research.

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“…A total of 3481 haplotypes from 21 previously reported populations [17][18][19][20][21][22][23][24][25][26][27][28] were selected for comparison through the 17 Y-STR loci (DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, YGATAH4, DYS437, DYS438, and DYS448). The genotype data of the 34 reference populations were obtained by the Yfiler V R , Yfiler V R Plus (Thermo Fisher Scientific, Waltham, MA, USA), PowerPlex V R Y23 (Promega Corporation, Madison, WI, USA), AGCU Y24 (AGCU Incorporation) and other available commercial Y-STR kits.…”

Section: Reference Populations and Previously Reported Y-str Datamentioning

confidence: 99%

Genetic polymorphisms and phylogenetic analyses of the Ü-Tsang Tibetan from Lhasa based on 30 slowly and moderately mutated Y-STR loci

Ding

Fan

Zhou

et al. 2020

Forensic Sciences Research

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As a result of the expansion of old Tibet on the Qinghai-Tibet Plateau, Tibetans diverged into three main branches, € U-Tsang, Amdo, and Kham Tibetan. € U-Tsang Tibetans are geographically distributed across the wide central and western portions of the Qinghai-Tibet Plateau while Lhasa is the central gathering place for Tibetan culture. The AGCU Y30, a 6dye fluorescence kit including 30 slowly and moderately mutated Y-STR loci, has been validated for its stability and sensitivity in different biomaterials and diverse Chinese populations (Han and other minorities), and widely used in the practical work of forensic science. However, the 30 Y-STR profiling of Tibetan, especially for € U-Tsang Tibetan, were insufficient. We utilized the AGCU Y30 to genotype 577 € U-Tsang Tibetan unrelated males from Lhasa in the Tibet Autonomous Region of China to fill up the full and accurate Y-STR profiles. A total of 552 haplotypes were observed, 536 (97.10%) of which were unique. One hundred and ninety-four alleles were observed at 26 single copy loci and the allelic frequencies ranged from 0.0017 to 0.8180. For the two multi-copy loci DYS385a/b and DYS527a/b, 64 and 36 allelic combinations were observed, respectively. The gene diversity (GD) values ranged from 0.3079 at DYS391 to 0.9142 at DYS385a/b and the overall haplotype diversity (HD) was 0.9998, and its discrimination capacity (DC) was 0.9567. The population genetic analyses demonstrated that Lhasa € U-Tsang Tibetan had close relationships with other Tibetan populations from Tibet and Qinghai, especially with € U-Tsang Tibetan. From the perspective of Y haplogroups, the admixture of the southward Qiang people with dominant haplogroup O-M122 and the northward migrations of the initial settlers of East Asia with haplogroup D-M175 hinted the Sino-Tibetan homologous, thus, we could not ignore the gene flows with other Sino-Tibetan populations, especially for Han Chinese, to characterize the forensic genetic landscape of Tibetan.

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Genetic diversities and phylogenetic analyses of three Chinese main ethnic groups in southwest China: A Y-Chromosomal STR study

Cited by 31 publications

References 59 publications

Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups

Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups

Population genetic analysis of 36 Y-chromosomal STRs yields comprehensive insights into the forensic features and phylogenetic relationship of Chinese Tai-Kadai-speaking Bouyei

Genetic polymorphisms and phylogenetic analyses of the Ü-Tsang Tibetan from Lhasa based on 30 slowly and moderately mutated Y-STR loci

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