Genetic diversity of Talpa europaea and Nova hantavirus (NVAV) in France

Hugot, Jean‐Pierre; Gu, Se Hun; Feliú, Carlos; Ventur, Jacint; Ribas, Alexis; Dormion, Jerôme; Yanagihara, Richard; Nicolas, Violaine

doi:10.4267/2042/54201

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…As previously stated, SWSV has been reported in S. araneus from neighboring countries [6,13]. In addition, high infection rates with every second animal being infected have been described in shrews in Finland [6], and moles in Poland and France for Mobatvirus novaense (Nova mobatvirus) [14,35]. Therefore, the detection of SWSV in S. araneus in Croatia is not unexpected.…”

Section: Discussionmentioning

confidence: 61%

First Molecular Evidence of Seewis Virus in Croatia

Svoboda Karić,

Anđelić Dmitrović,

Mrmić

et al. 2023

Life

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Orthohantaviruses are mainly carried and transmitted by wild rodents, although during the last decade, they have also been identified in multiple species of shrews and moles. Orthohantavirus, Orthohantavirus seewisense (Seewis virus, SWSV), first detected in Switzerland in a single Sorex araneus (Eurasian common shrew) specimen, has been further described in several European countries, including Croatia’s neighboring Slovenia and Hungary. Croatia is a well-known endemic region for several zoonotic agents including three different orthohantaviruses: Orthohantavirus puumalaense (PUUV), Orthohantavirus dobravaense (DOBV), and Orthohantavirus tulaense (TULV). In this study, nine shrews were tested and SWSV RNA was detected in liver, lung, and kidney belonging to two shrews (22.22%), one collected on Medvednica mountain in Zagreb County, and the other in the Stara Gradiška area in lowland Croatia. The phylogenetic analysis of the complete S segment’s open reading frame (ORF) and partial L-segment revealed that the Croatian sequences, when compared to sequences from the adjacent geographic regions, form a specific genetic lineage. Two SWSV-positive shrew species—Sorex araneus and Neomys milleri (Mediterranean water shrew)—were identified using barcode-based sequence analysis. Therefore, the SWSV detection in N. milleri throughout the course of this study is seen as a rare find in this shrew species. To our knowledge, this is the first molecular and phylogenetic analysis of SWSV in Croatia.

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Section: Discussionmentioning

confidence: 61%

First Molecular Evidence of Seewis Virus in Croatia

Svoboda Karić,

Anđelić Dmitrović,

Mrmić

et al. 2023

Life

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A Novel Hantavirus of the European Mole, Bruges Virus, Is Involved in Frequent Nova Virus Coinfections

Laenen

Vergote

Kafetzopoulou

et al. 2017

Genome Biology and Evolution

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Hantaviruses are zoonotic viruses with a complex evolutionary history of virus–host coevolution and cross-species transmission. Although hantaviruses have a broad reservoir host range, virus–host relationships were previously thought to be strict, with a single virus species infecting a single host species. Here, we describe Bruges virus, a novel hantavirus harbored by the European mole (Talpa europaea), which is the well-known host of Nova virus. Phylogenetic analyses of all three genomic segments showed tree topology inconsistencies, suggesting that Bruges virus has emerged from cross-species transmission and ancient reassortment events. A high number of coinfections with Bruges and Nova viruses was detected, but no evidence was found for reassortment between these two hantaviruses. These findings highlight the complexity of hantavirus evolution and the importance of further investigation of hantavirus–reservoir relationships.

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Karyotype Analysis of the New Talpa Species Talpa aquitania (Talpidae; Insectivora) from Northern Spain

Gutiérrez¹,

Aleix-Mata²,

Lamelas³

et al. 2019

Cytogenet Genome Res

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Karyotypes of 3 male Talpa specimens from northern Spain were analyzed. The mesostyles of upper molars and cytochrome b sequence analysis identified these specimens as belonging to Talpa aquitania, a new Talpa species recently described from northern Spain and southern France. We describe here for the first time the karyotype of Talpa aquitania. Its diploid number is 2n = 34 and NFa = 64, and all chromosomes including the sex chromosomes are biarmed, either metacentric or submetacentric. G-banding demonstrated that the karyotypes of T. aquitania and T. occidentalis (the most closely related species) are almost identical. However, the karyotype of T. aquitania differs from the karyotypes of both T. europaea and T. occidentalis in that it has a medium-sized biarmed Y chromosome rather than a dot-like chromosome and that chromosome 16 is submetacentric in T. aquitania but has a small p-arm in both T. europaea and T. occidentalis. Pericentromeric C-bands were scarce and only clearly visible in a few chromosomal pairs. In addition, C-banding demonstrated that half of the 14p, the 16p, and the Y chromosome are all heterochromatic. rDNA genes were located at the secondary constriction in autosomal pair 3, a common feature in the karyotypes of all Talpa species. Hybridization signals for telomeric repeats were found on the telomeres and the pericentric regions of some chromosomes and co-localized in the secondary constriction of pair 3 with the rDNA genes. In conclusion, the karyotype of T. aquitania from northern Spain is very similar to the karyotype of other species belonging to the genus Talpa.

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Genetic diversity of Talpa europaea and Nova hantavirus (NVAV) in France

Cited by 3 publications

References 19 publications

First Molecular Evidence of Seewis Virus in Croatia

First Molecular Evidence of Seewis Virus in Croatia

A Novel Hantavirus of the European Mole, Bruges Virus, Is Involved in Frequent Nova Virus Coinfections

Karyotype Analysis of the New <b><i>Talpa</i></b> Species <b><i>Talpa aquitania</i></b> (Talpidae; Insectivora) from Northern Spain

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