Genetic diversity of two Tibetan macaque (Macaca thibetana) populations from Guizhou and Yunnan in China based on mitochondrial DNA D-loop sequences

Zhong, Lijing; Zhang, Ming-Wang; Yao, Yongfang; Ni, Qingyong; Mu, Jun; Li, Chong-Qing; Xu, Huailiang

doi:10.1007/s13258-012-0048-2

Cited by 11 publications

(13 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…; Zhong et al. ). However, the population size of these two macaque species in China are still large (7000 M. thibetana , 77000 M. mulatta ); thus, these macaques are not regarded as endangered.…”

Section: Discussionmentioning

confidence: 97%

“…; Zhong et al. ). However, the number of M. mulatta and M. thibetana in China is relatively large relative to the number of snub‐nosed monkeys and langurs.…”

Section: Introductionmentioning

confidence: 97%

“…; Zhong et al. ). Furthermore, macaques are likely to adapt to the anthropogenic environment (Gumert ), whereas other primates (snub‐nosed monkeys, langurs, gibbons) are negatively affected by human activities.…”

Section: Introductionmentioning

confidence: 97%

“…Few publications address the conservation genetics of Chinese primates. There are publications on the population genetics of Macaca mulatta and M. thibetana in China that include conservation recommendations (Wu et al 2013;Yao et al 2013;Zhong et al 2013). However, the number of M. mulatta and M. thibetana in pr1-pr5]).…”

mentioning

confidence: 99%

See 3 more Smart Citations

Implications of genetics and current protected areas for conservation of 5 endangered primates in China

Liu

Roos

et al. 2015

Conservation Biology

View full text Add to dashboard Cite

Most of China's 24-28 primate species are threatened with extinction. Habitat reduction and fragmentation are perhaps the greatest threats. We used published data from a conservation genetics study of 5 endangered primates in China (Rhinopithecus roxellana, R. bieti, R. brelichi, Trachypithecus francoisi, and T. leucocephalus); distribution data on these species; and the distribution, area, and location of protected areas to inform conservation strategies for these primates. All 5 species were separated into subpopulations with unique genetic components. Gene flow appeared to be strongly impeded by agricultural land, meadows used for grazing, highways, and humans dwellings. Most species declined severely or diverged concurrently as human population and crop land cover increased. Nature reserves were not evenly distributed across subpopulations with unique genetic backgrounds. Certain small subpopulations were severely fragmented and had higher extinction risk than others. Primate mobility is limited and their genetic structure is strong and susceptible to substantial loss of diversity due to local extinction. Thus, to maximize preservation of genetic diversity in all these primate species, our results suggest protection is required for all sub-populations. Key priorities for their conservation include maintaining R. roxellana in Shennongjia national reserve, subpopulations S4 and S5 of R. bieti and of R. brelichi in Fanjingshan national reserve, subpopulation CGX of T. francoisi in central Guangxi Province, and all 3 T. leucocephalus sub-populations in central Guangxi Province.

show abstract

Section: Discussionmentioning

confidence: 97%

“…; Zhong et al. ). However, the number of M. mulatta and M. thibetana in China is relatively large relative to the number of snub‐nosed monkeys and langurs.…”

Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 97%

mentioning

confidence: 99%

See 2 more Smart Citations

Implications of genetics and current protected areas for conservation of 5 endangered primates in China

Liu

Roos

et al. 2015

Conservation Biology

View full text Add to dashboard Cite

show abstract

“…Recently, studies on the Tibetan macaque have primarily focused on its ethology (Zhao, 1997;Li et al, 2007;Xia et al, 2012Xia et al, , 2013, rearing, and disease prevention (Zhong et al, 2010;Wu et al, 2013). In molecular genetics, only a small number of studies on mitochondrial DNA (Li et al, 2008(Li et al, , 2009Yao et al, 2013a;Zhong et al, 2013), microsatellite DNA (Jia et al, 2011(Jia et al, , 2012, and immunity genes Yao et al, 2013b;Liu et al, 2013) have been reported.…”

Section: Introductionmentioning

confidence: 99%

Sequence characterization and phylogenetic analysis of toll-like receptor (TLR) 4 gene in the Tibetan macaque (Macaca thibetana)

Dai

Yao

et al. 2015

Genet. Mol. Res.

View full text Add to dashboard Cite

ABSTRACT. In this study, the complete coding region sequence of an innate immune-related TLR4 gene was obtained from the Tibetan macaque (Macaca thibetana) genome via PCR and direct sequencing. The sequence had a total length of 2481 bp, contained 3 complete exons, and encoded 826 amino acids (AAs); its isoelectric point was 5.703, and the molecular weight was 94.72 kDa. The high structure prediction showed that the protein was comprised of one extracellular region, one transmembrane region, and one intracellular region. There were 48 potential functional sites in the protein, including glycosylation, phosphorylation, and acetylation sites. A homology analysis among 9 primate species, including the Tibetan macaque, human, chimpanzee, gibbon, rhesus macaque, cynomolgus monkey, pig-tailed monkey, squirrel monkey, and small-eared galago, showed that the homology of the nucleotide and AA sequences ranged from 60.9-99.5% and 51.4-99.0%, respectively. Higher variability was identified in the extracellular region of the TLR4 protein, and its variable sites accounted for 88.79% (AA) of the total variable sites. Additionally, the number of AAs at the 3' end of the intracellular region was notably different among the primate lineages. The phylogenetic tree based on TLR4 gene exons of 9 primate species showed that the Tibetan macaque clustered with the rhesus macaque, cynomolgus monkey, and pig-tailed monkey; it was most distant from the small-eared galago. This study will provide an important basis for further study on the expression, regulation, and polymorphism of the TLR4 gene and the relationship between polymorphisms and host disease susceptibility.

show abstract

Mitochondrial DNA analyses and ecological niche modeling reveal post‐LGM expansion of the Assam macaque (Macaca assamensis) in the foothills of Nepal Himalaya

Khanal

Chalise

et al. 2018

American J Primatol

View full text Add to dashboard Cite

Genetic diversity of a species is influenced by multiple factors, including the Quaternary glacial-interglacial cycles and geophysical barriers. Such factors are not yet well documented for fauna from the southern border of the Himalayan region. This study used mitochondrial DNA (mtDNA) sequences and ecological niche modeling (ENM) to explore how the late Pleistocene climatic fluctuations and complex geography of the Himalayan region have shaped genetic diversity, population genetic structure, and demographic history of the Nepalese population of Assam macaques (Macaca assamensis) in the Himalayan foothills. A total of 277 fecal samples were collected from 39 wild troops over almost the entire distribution of the species in Nepal. The mtDNA fragment encompassing the complete control region (1121 bp) was recovered from 208 samples, thus defining 54 haplotypes. Results showed low nucleotide diversity (0.0075 ± SD 0.0001) but high haplotype diversity (0.965 ± SD 0.004). The mtDNA sequences revealed a shallow population genetic structure with a moderate but statistically significant effect of isolation by distance. Demographic history analyses using mtDNA sequences suggested a post-pleistocene population expansion. Paleodistribution reconstruction projected that the potential habitat of the Assam macaque was confined to the lower elevations of central Nepal during the Last Glacial Maximum. With the onset of the Holocene climatic optimum, the glacial refugia population experienced eastward range expansion to higher elevations. We conclude that the low genetic diversity and shallow population genetic structure of the Assam macaque population in the Nepal Himalaya region are the consequence of recent demographic and spatial expansion.

show abstract

Genetic diversity of two Tibetan macaque (Macaca thibetana) populations from Guizhou and Yunnan in China based on mitochondrial DNA D-loop sequences

Cited by 11 publications

References 39 publications

Implications of genetics and current protected areas for conservation of 5 endangered primates in China

Implications of genetics and current protected areas for conservation of 5 endangered primates in China

Sequence characterization and phylogenetic analysis of toll-like receptor (TLR) 4 gene in the Tibetan macaque (Macaca thibetana)

Mitochondrial DNA analyses and ecological niche modeling reveal post‐LGM expansion of the Assam macaque (Macaca assamensis) in the foothills of Nepal Himalaya

Contact Info

Product

Resources

About