Genetic mechanisms in the intergenerational transmission of health

Adolescence and the next generation

“…Here we explore the range of adolescent processes-molecular, physio logical, behavioural and sociocultural-that may affect the early growth, health and development of the next generation [19][20][21] (Fig. 1).…”

The intergenerational transmission of human capital: the role of skills and health

“…Corak and Piraino (2011) study the intergenerational transmission of employers. Thompson (2014) studies the transmission of health and Cesarini et al (2014) study the transmission of voting behaviour.…”

Breaking the Intergenerational Cycle of Disadvantage: The Three Generation Approach

“…Recognizing the key role environments play in modulating gene expression, today the transmission of health and well-being across generations is understood as a function of gene-environment interactions that occur in a specific shared context. 21 Although it is understood that the environments of families who experience multigenerational disadvantage are often characterized by high levels of psychosocial and physical stressors and lack of buffering resources, how these environments get under the skin to create health disparities remains puzzling. Over the past 2 decades, multiple frameworks have been used to understand these mechanisms.…”

“…48 Children raised in poverty often fail to accumulate the "health capital" that facilitates later educational attainment, peer relationships, and ability to parent, all of which contribute substantially to LCHD and transmission of health risk across generations. 21,49,50 Today's widening education gap suggests that the contribution of adolescent capacities (or lack thereof) to population-level patterns of generational disadvantage is arguably greater now than in the past. 49 Thus, a child (G2) born to poor parents (G1) is likely to remain poor as an adult (G2) and, if he or she becomes a parent, to raise poor children (G3).…”