Genetic polymorphisms of eight X-chromosomal STR loci in the population of Japanese

Tie, Jian; Uchigasaki, Seisaku; Oshida, Shigemi

doi:10.1016/j.fsigen.2009.09.002

Cited by 18 publications

(11 citation statements)

References 11 publications

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“…DXS7423 had the lowest values based on the forensic parameters. The Japanese allele frequencies of 11 XSTRs (excluding DXS10147) showed no significant difference as compared with other Japanese populations [3,5,21,22]. However, the results for DXS10147 were different from previous reports on German populations [13].…”

Section: Resultscontrasting

confidence: 77%

Application of a novel multiplex polymerase chain reaction system for 12 X-chromosomal short tandem repeats to a Japanese population study

et al. 2013

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Section: Resultscontrasting

confidence: 77%

Application of a novel multiplex polymerase chain reaction system for 12 X-chromosomal short tandem repeats to a Japanese population study

et al. 2013

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“…Pairwise F ST values for each X-STR were calculated between a variable number of populations, depending on the X-STR system. Pairwise F ST values based on eight of the 12 studied X-STRs (DXS10135, DXS8378, DXS7132, DXS10074, HPRTB, DXS10101, DXS10134 and DXS7423) calculated for 14 populations in Denmark, Greenland and Somalia (present study), Germany [14], Italy [15], Algeria [16], Finland [17], Somalia [17], Hungary [18,19], Korea [20], Ghana [21], Poland [22], Japan [23] and China [24] were averaged over loci and represented in a multidimensional scaling (MDS) plot using the statistical package SPSS v.15.0.…”

Section: Discussionmentioning

confidence: 80%

Analysis of 12 X-STRs in Greenlanders, Danes and Somalis using Argus X-12

2011

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X-chromosome markers have become a useful set of markers of choice when certain complex kinship cases need to be unravelled. The Argus X-12 kit allows the co-amplification in a single PCR reaction of 12 X-chromosome short tandem repeats located in four linkage groups. A number of 507 unrelated individuals from Greenland, Denmark and Somalia together with two generation families were typed using the Argus X-12 kit. Silent alleles for the DXS10148 and DXS10146 systems were observed in males, mostly from Somalia. High levels of intrapopulation variability and therefore high forensic parameter values were calculated for the three studied populations. The population in Greenland showed a significantly lower intrapopulation variability and a high genetic differentiation compared with 13 other populations. Significant levels of linkage disequilibrium were observed between markers belonging to the same linkage group, mainly in the populations in Greenland and Somalia. Family studies allowed the calculation of mutation and recombination frequencies. A higher male versus female mutation rate was obtained, with an average value of 3.3 × 10(-3). Recombination fraction calculations performed on two generation families showed, as previously described, a not complete independence between X-chromosome linkage groups 3 and 4.

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“…In addition, four (DXS8378, DXS7132, HPRTB, and DXS7423) of the eight loci had been examined in the Japanese population by in-house multiplex PCR [17,18]. Only DXS10135 showed a significant difference in allelic frequency between that observed in these earlier reports in Japanese populations of similar size (P=0.0007 and P=0.0100 for Tamura et al [14] and Tie et al [15], respectively), while only DXS10135 and DXS7132 showed a significant difference in a Korean population [16]. However, significant differences were observed in all eight loci between the present data and those of Germans [13].…”

Section: Resultsmentioning

confidence: 87%

“…Although the degree of diversity differed depending on the parameters (Table S1), most of the loci in the Argus X-8 kit were fairly informative in the Japanese population. Four earlier studies using the Argus X-8 kit to examine the same loci targeted in this study in East Asian populations were found, three on Japanese populations [13][14][15] and one on a Korean population [16]. In addition, four (DXS8378, DXS7132, HPRTB, and DXS7423) of the eight loci had been examined in the Japanese population by in-house multiplex PCR [17,18].…”

Section: Resultsmentioning

confidence: 88%

Population genetic study of six closely linked groups of X-STRs in a Japanese population

2011

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X chromosome STR (X-STR) polymorphisms are a useful tool in the fields of human population genetics and personal identification and are quite informative in the investigation of complex kinship or deficiency cases, especially where it is necessary to determine relationships with second-generation offspring in which the same X chromosome may have been inherited. We investigated eight X-STR systems using the Mentype Argus X-8 kit and further developed decaplex PCR for the DXS10148, DXS10161, DXS10160, DXS10159, DXS10079, DXS10075, DXS6799, DXS10102, DXS10106, and DXS10146 loci with the aim of constructing closely linked groups on the X chromosome. The studied population comprised 569 Japanese individuals (390 males and 179 females). Heterozygosity among the present 18 X-STRs showed a distribution of from 54.2% to 90.5%. We constructed six closely linked groups, each comprising three to five X-STRs: DXS10148-DXS10135-DXS8378, DXS10161-DXS10160-DXS10159, DXS7132-DXS10079-DXS10074-DXS10075-DXS981, DXS6809-DXS6789-DXS6799, DXS10102-HPRTB-DXS10101-DXS10106, and DXS8377-DXS10146-DXS10134-DXS7423. The forensic utility of these groups as haplotypes was then evaluated. Haplotype diversity values showed a distribution of from 0.9699 to 0.9959. Analysis of the present closely linked haplotypes will contribute to solving complex kinship cases involving X chromosome inheritance.

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Genetic polymorphisms of eight X-chromosomal STR loci in the population of Japanese

Cited by 18 publications

References 11 publications

Application of a novel multiplex polymerase chain reaction system for 12 X-chromosomal short tandem repeats to a Japanese population study

Application of a novel multiplex polymerase chain reaction system for 12 X-chromosomal short tandem repeats to a Japanese population study

Analysis of 12 X-STRs in Greenlanders, Danes and Somalis using Argus X-12

Population genetic study of six closely linked groups of X-STRs in a Japanese population

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