Genetic population data of three Y-STR genetic systems in Mexican-Mestizos from Monterrey, Nuevo León (Northeast, Mexico)

Ramos-González, Benito; Aguilar-Velázquez, José Alonso; Chávez-Briones, María de Lourdes; Escareño-Hernández, María del Rocío; Alfaro-Lopez, Elizabeth; Rangel-Villalobos, Héctor

doi:10.1016/j.fsigen.2017.04.016

Cited by 9 publications

(1 citation statement)

References 13 publications

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“…Also, our RSB results improve importantly the combined PD and CE compared with those previously obtained in Monterrey City but based on 23 aSTRs genotyped by CE [19]. As expected, our sequencing results for the 24 Y-STRs also improve the genetic informativity from Monterrey City regarding that previously reported with 23 Y-STRs based on CE, where a discriminatory capacity of 93.75 % was described [20]. Although our sample size is smaller, with sequencing results a higher discriminatory capacity is expected due to RSB variation.…”

Section: Discussionsupporting

confidence: 84%

Characterization of 58 STRs and 94 SNPs with the ForenSeq™ DNA Signature Prep Kit in Mexican-Mestizos from the Monterrey City (Northeast, Mexico)

Aguilar-Velázquez

Duran-Salazar

Córdoba-Mercado³

et al. 2021

Preprint

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Background. STR allele frequency databases from populations are necessary to take full advantage of the increased power of discrimination offered by massive parallel sequencing (MPS) platforms.Material and methods. For this reason, we sequenced 58 STRs (aSTRs, X-STRs, and Y-STRs) and 94 identity informative SNPs (iiSNPs) on 105 Mestizo (admixed) individuals from Monterrey City (Northeast, Mexico), with the Primer Set-A of the ForenSeqTM DNA Signature Prep Kit. Results. Most of the STR markers were in Hardy Weinberg equilibrium, with a few exceptions. We found 346 different length-based alleles for these 58 STRs; nevertheless, they became 528 alleles when the sequence was assessed. The combined power of discrimination from autosomal STRs (aSTRs) was –virtually– 100 % in both length and sequence-based alleles, while the power of exclusion were 99.9999999976065 and 99.9999999999494%, respectively. Haplotypes based on X-STRs and Y-STRs showed 100% of discriminatory capacity. Conclusion. These results provide –for the first time– forensic genomic population data from Mexico necessary for interpretation in kinship and criminal analyses.

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Section: Discussionsupporting

confidence: 84%