Genetic variation at RYR1, IGF2, FUT1, MUC13, and KPL2 mutations affecting production traits in Chinese commercial pig breeds

Ruan, Guo‐Rui; Xing, Y. Y.; Fan, Yinglun; Qiao, Ruimin; He, Xue-Lian; Yang, Bin; Ding, Nengshui; Ren, Jun; Huang, Lusheng; Xiao, Shijun

doi:10.17221/6616-cjas

Cited by 11 publications

(8 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The studies of pig allele pool for IGF2 revealed differences in the distribution of allele and genotype frequencies in the animals depending on the specialization and breeding character. Maximum A allele frequencies (desirable from the point of view of development of meat and fattening traits) were observed in pigs of meat breeds (Body, Duroc, Pietrain) and in the terminal cross characterized by the maximum selection intensity for the above traits, which is consistent with the results of foreign authors [13,[18][19][20]. In mother breed pigs (Large White, Landrace) and the ones produced by improving local breeds with meat breeds (Belorussian meat, Estonian bacon), intermediate A allele frequencies have been recorded.…”

Section: The Results Of One-way Anova Evaluating the Effect Of Fathersupporting

confidence: 90%

The Association of Igf2 With Productive Traits of Pigs of Large White Breed in the Aspect of Sexual Differentiation

Kostyunina¹,

Крамаренко²,

Свеженцева³

et al. 2015

S-h. biol.

View full text Add to dashboard Cite

A b s t r a c tMarker-assisted selection is an attractive way to improve the economically important traits in domestic animals and particularly in pigs. Insulin-like growth factor 2 (IGF2) is one of the potentially important genetic marker for growth and carcass traits of pigs. The objective of our work was to study G3072A polymorphism of IGF2 gene in different pig breeds and to evaluate the effect of boar genotypes on productive traits of their offspring of different sexes. IGF2 polymorphism was studied in seven pig breeds including large white and their close related breeds Yorkshire and Edelswine (LW, n = 1247), Landrace (L, n = 934), Duroc (D, n = 642), Pietrain (P, n = 87), Belorussian meat (BM, n = 37), Liven (LIV, n = 54), Estonian beckon (EB, n = 10), one synthetic line Body (BD, n = 138) and one terminal cross (TM, n = 66). Association studies were performed using data records of 5908 offspring (including 5015 gilts and 893 young boars) produced from twenty LW boars with known genotype for IGF2. The following productive traits were evaluated: body weight at the end of growing period (BW, kg), daily gain during entire growing period (DG, g), daily gain during early period from birth to 76.41±0.04 days (DG1, g), daily gain during late period from 76.41±0.04 to 170.23±0.05 (DG2, g); the age at 100 kg (AGE 100kg , days), average actual back fat thickness measured in four points at the end of growing period (BF, mm) and average back fat thickness calculated for the 100 kg body weight (BF 100kg , mm). Significantly higher frequencies of the potentially «desired» A allele and AA genotype were observed in BD (0.986 and 0.971, respectively), ТМ (0.977 and 0.955), P (0.966 and 0.931) and D (0.960 and 0.921). LW pigs were characterized by the intermediate values of allele A (0.664) and genotype AA frequencies (0.532). In EB, BM and L the frequencies of A allele and AA genotype varied from 0.250 to 0.363 and from 0.100 to 0.243, respectively. We did not identify A allele in local Russian LIV pig breed. Association studies showed high-significant tendency to increase of BW, DG1, DG2, DG, BF and BF 100kg values and to decrease of AGE 100kg values of both gilts and boars at the order of genotypes GG → AG → AA. Calculations performed with additive-dominance model and two-way analysis of variance (ANOVA) showed the faster increasing (decreasing) above-mentioned traits in order of genotypes GG → AG → AA in young boars comparing to gilts. Principal component (PC) analysis showed that first two PCs (PC1 and PC2) determine 76.23 % of variability of the initial matrix for young boars and 82.49 % for gilts. PC1 is highly associated with daily gains during the late growing period (for DG2: r = 0.501 for young boars and 0.896 for gilts) and for the entire growing period (for DG: r = 0.923 and 0.929), whereas PC2 is associated with the daily gains during early growing period (for DG1: r = 0.709 and 0.769). The additive (A) and dominant (D) components of the variability and effects of allele substitution calculated for PC1 were ...

show abstract

Section: The Results Of One-way Anova Evaluating the Effect Of Fathersupporting

confidence: 90%

The Association of Igf2 With Productive Traits of Pigs of Large White Breed in the Aspect of Sexual Differentiation

Kostyunina¹,

Крамаренко²,

Свеженцева³

et al. 2015

S-h. biol.

View full text Add to dashboard Cite

show abstract

“…As a consequence, the effects of the variability at the LEP gene on meat quality and carcase traits should be also analysed in the NL pig population. Table 3 shows the comparison between the allele frequencies calculated according to the typing results of the NL pig and the data available in literature for the cosmopolitan (Pietrain, Duroc, Large White and Landrace) breeds (Stratil et al 1997;Kennes et al 2001;Kim et al 2005a;Piorkowska et al 2010;Aslan et al 2012;Burgos et al 2012;Davoli et al 2012;Ruan et al 2013;Fan et al 2013;Hirose et al 2014;Ilie et al 2014). As a whole, the average heterozygosity of the NL pig population, at the 12 considered loci, showed a very low value of 0.157.…”

Section: Resultsmentioning

confidence: 99%

Genetic variability of Nero Lucano pig breed at IGF2, LEP, MC4R, PIK3C3, RYR1 and VRTN loci

Valluzzi

Rando

Gregorio

2019

Italian Journal of Animal Science

View full text Add to dashboard Cite

The Nero Lucano pig is a native breed of Southern Italy which thanks to the joint action of Basilicata Region Institutions, University of Basilicata and breeders returned to populate the area of origin. In order to characterise and to monitor the variability present in the population, we genotyped 229 animals at 12 polymorphic loci located in the following genes: IGF2, LEP, MC4R, PIK3C3, RYR1 and VRTN. According to the results three loci (IGF2 209G>C, PIK3C3 2058A>G and RYR1 1843C>T) did not show variability, while the others showed genotype distributions in agreement with Hardy-Weinberg equilibrium and a minor allele frequency ranging from 0.022 for MC4R 892A to 0.479 for PIK3C3 2604T alleles. The IGF2, MC4R and VRTN loci were characterised by very low frequencies (from 0.02 to 0.05) of the alleles that are associated with favourable productive characteristics in cosmopolitan breeds. HIGHLIGHTS Analyses of the genetic variability of Nero Lucano pig population useful for meat production selection plans. The IGF2, MC4R and VRTN loci of Nero Lucano pig show very low frequencies of alleles associated with positive effects on meat production. The Nero Lucano pig can be considered as free from Malignant Hyperthermia, a positive result for the quality of cured meat products.

show abstract

“…Genomic DNA was extracted from muscle samples using GeneMATRIX Tissue DNA Purification Kit (EURx, Poland). The RYR1 polymorphism was analyzed by polymerase chain reaction-restriction fragment length polymorphism method (PCR-RFLP) using following primer sequences: RYR1_F 5'-TCCAGTTTGCCACAGGTCCTACCA-3'; RYR1_R-5'-ATTCACCGGAGTGGAGTCTCTGAG-3' (Ruan et al 2013). Identification of the stress sensitivity gene (RYR1) revealed the occurrence of individuals with heterozygous genotype (CT) only in the group of fatteners derived from Pulawska breed boars (n = 2).…”

Section: Polymorphism Of the Ryr1 Genementioning

confidence: 99%

The effect of DanAvl Duroc and Pulawska boars in crossbred with DanAvl Hybrid on meat quality of finishing pigs

Rybarczyk

Moroch

Polasik

2018

AFSci

View full text Add to dashboard Cite

The research was aimed at determining the physicochemical and sensory properties of the m. longissimus lumborum at DanAvl Hybrid (Landrace – Yorkshire) fatteners and derived from DanAvl Hybrid sows and DanAvl Duroc and Pulawska boars. Fatteners derived from DanAvl Duroc boars were characterized by better meat quality compared to DanAvl Hybrids and their hybrids with Pulawska breed as evidenced by higher pH in 24–96 h post mortem (p.m.), higher sensory evaluation of juiciness, tenderness and flavor as well as lower shear force at lower content of total protein and higher content of intramuscular fat (IMF). However, DanAvl Hybrid fatteners were characterized by poorer meat quality, i.e. higher color lightness (L*) and higher drip loss both from fresh and thawed meat compared to those derived from DanAvl Duroc and Pulawska boars. Meat of fatteners after Pulawska breed was characterized by the highest redness (a*), and that after DanAvl Duroc breed, the lowest yellowness (b*) and saturation (C*).

show abstract

Genetic variation at RYR1, IGF2, FUT1, MUC13, and KPL2 mutations affecting production traits in Chinese commercial pig breeds

Cited by 11 publications

References 21 publications

The Association of Igf2 With Productive Traits of Pigs of Large White Breed in the Aspect of Sexual Differentiation

The Association of Igf2 With Productive Traits of Pigs of Large White Breed in the Aspect of Sexual Differentiation

Genetic variability of Nero Lucano pig breed at IGF2, LEP, MC4R, PIK3C3, RYR1 and VRTN loci

The effect of DanAvl Duroc and Pulawska boars in crossbred with DanAvl Hybrid on meat quality of finishing pigs

Contact Info

Product

Resources

About