Genome Sequence of Porphyromonas gingivalis Strain AJW4

Abstract

Porphyromonas gingivalis is associated with oral and systemic diseases. Strain-specific P. gingivalis invasion phenotypes have been correlated with disease presentation in infected laboratory animals. Here, we present the genome sequence of AJW4, a minimally invasive strain, with a single contig of 2,372,492 bp and a G+C content of 48.27%.

Genome Sequence of Porphyromonas gingivalis Strain A7A1-28

“…This has extended to genome sequencing: fimbrillin type I, capsule absent ( 15 , 17 , 19 ) (ATCC 33277 [ 20 ] and 381 [ 21 ]), and fimbrillin type IV, capsule K1 ( 15 , 17 , 22 , 23 ) (W83 [ 24 ] and A7436 [ 25 ]). Fimbrillin and capsule information is unavailable for other sequenced laboratory strains of P. gingivalis ( 26 – 28 ). A7A1-28 is a widely available strain that exhibits fimbrillin type II and capsule K3 ( 15 , 17 , 19 ).…”

Clinical significance of ragA, ragB, and PG0982 genes in Porphyromonas gingivalis isolates from periodontitis patients

“…gingivalis virulence, as can be seen in invasive wild type P . gingivalis (W83) [31], and in ATCC 33277, A7436, 381, TDC60, HG66, A7A1‐28, and the only non‐invasive AJW4 strain [32–36]. However, even strains that share the same genes do not exhibit the same virulence.…”